Microbial Keratitis Profile at a University Hospital in Hong Kong

Purpose. To evaluate the recent trends in demographics, risk factors, and microbiological profiles of microbial keratitis at a university hospital in Hong Kong. Design. Retrospective review. Methods. The medical records of 51 patients admitted to the Prince of Wales Hospital for microbial keratitis...

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Bibliographic Details
Published in:International scholarly research notices 2014, Vol.2014, p.689742-4
Main Authors: Lai, Tracy H. T., Jhanji, Vishal, Young, Alvin L.
Format: Article
Language:English
Subjects:
Age
Antibiotics
Clinical Study
Contact lenses
Demographic aspects
Diagnosis
Fungal infections
Gram-positive bacteria
Keratitis
Pathogens
Patients
Risk factors
Studies
Ulcers
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Summary:Purpose. To evaluate the recent trends in demographics, risk factors, and microbiological profiles of microbial keratitis at a university hospital in Hong Kong. Design. Retrospective review. Methods. The medical records of 51 patients admitted to the Prince of Wales Hospital for microbial keratitis from January 2010 to June 2012 were reviewed. Demographics, risk factors, clinical features, microbiological results, and treatment were recorded. Data was analyzed and compared to our historical sampled data collected 11 years ago. Results. The mean age of patients was 41.6 ± 20.3 years. Contact lens use was the major risk factor (45%), followed by injury (12%). The culture positive rate was 59%, of which 37% were Gram-positive organisms and 53% were Gram-negative organisms. Pseudomonas aeruginosa (50%) and coagulase-negative Staphylococcus (13%) were the most commonly isolated pathogens. No resistance to fluoroquinolones was identified. Conclusions. Our study showed that contact lens wear remained the major risk factor for microbial keratitis in Hong Kong and Pseudomonas aeruginosa remained the commonest bacterium isolated. This is comparable to our historical data and other studies conducted in East Asia.
ISSN:2356-7872
2356-7872
DOI:10.1155/2014/689742