Principles for designing synthetic microbial communities

Highlights • Synthetic microbial communities have many potential uses in industrial biotechnology. • Defined intercellular and spatiotemporal coordination enable precise consortia engineering. • Community robustness and stability should be assessed and designed into synthetic systems. • Deployment o...

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Bibliographic Details
Published in:Current opinion in microbiology 2016-06, Vol.31, p.146-153
Main Authors: Johns, Nathan I, Blazejewski, Tomasz, Gomes, Antonio LC, Wang, Harris H
Format: Article
Language:English
Subjects:
Biodegradation, Environmental
Biotechnology
Ecosystem
Genetic Engineering
Microbial Consortia - genetics
Microbial Interactions - physiology
Organisms, Genetically Modified - genetics
Organisms, Genetically Modified - growth & development
Organisms, Genetically Modified - metabolism
Pathology
Synthetic Biology - methods
Systems Biology - methods
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Summary:Highlights • Synthetic microbial communities have many potential uses in industrial biotechnology. • Defined intercellular and spatiotemporal coordination enable precise consortia engineering. • Community robustness and stability should be assessed and designed into synthetic systems. • Deployment of biocontainment and population control measures are needed for real-world applications.
ISSN:1369-5274
1879-0364
DOI:10.1016/j.mib.2016.03.010