Pathologic aspects of skull base tumors

Abstract Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, a...

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Bibliographic Details
Published in:Reports of practical oncology and radiotherapy 2016-07, Vol.21 (4), p.288-303
Main Authors: Marszałek, Andrzej, Szylberg, Łukasz, Wiśniewski, Sławomir
Format: Article
Language:English
Subjects:
Benign
Hematology, Oncology and Palliative Medicine
Histopathology
Malignant
Radiology
Review
Skull base tumors
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Summary:Abstract Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.
ISSN:1507-1367
2083-4640
DOI:10.1016/j.rpor.2016.02.006