Volumetric (3D) bladder dose parameters are more reproducible than point (2D) dose parameters in vaginal vault high-dose-rate brachytherapy

There is no consensus on the use of computed tomography in vaginal cuff brachytherapy (VCB) planning. The purpose of this study was to prospectively determine the reproducibility of point bladder dose parameters (D ICRU and maximum dose), compared with volumetric-based parameters. Twenty-two patient...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2016-06, Vol.6 (1), p.28074-28074, Article 28074
Main Authors: Sapienza, Lucas Gomes, Flosi, Adriana, Aiza, Antonio, de Assis Pellizzon, Antonio Cassio, Chojniak, Rubens, Baiocchi, Glauco
Format: Article
Language:English
Subjects:
692/4028/67/1517/1371
692/4028/67/1517/1931
Bladder
Cancer therapies
Catheters
Cervical cancer
Computed tomography
Dosimetry
Humanities and Social Sciences
Medical imaging
Medical instruments
multidisciplinary
Oncology
Patients
Planning
Radiation therapy
Reproducibility
Science
Science (multidisciplinary)
Tension
Toxicity
Vagina
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There is no consensus on the use of computed tomography in vaginal cuff brachytherapy (VCB) planning. The purpose of this study was to prospectively determine the reproducibility of point bladder dose parameters (D ICRU and maximum dose), compared with volumetric-based parameters. Twenty-two patients who were treated with high-dose-rate (HDR) VCB underwent simulation by computed tomography (CT-scan) with a Foley catheter at standard tension (position A) and extra tension (position B). CT-scan determined the bladder ICRU dose point in both positions and compared the displacement and recorded dose. Volumetric parameters (D0.1cc, D1.0cc, D2.0cc, D4.0cc and D50%) and point dose parameters were compared. The average spatial shift in ICRU dose point in the vertical, longitudinal and lateral directions was 2.91 mm (range: 0.10–9.00), 12.04 mm (range: 4.50–24.50) and 2.65 mm (range: 0.60–8.80), respectively. The D ICRU ratio for positions A and B was 1.64 ( p  
ISSN:2045-2322
2045-2322
DOI:10.1038/srep28074