A Case Report: The Diagnosis and Therapeutic Evaluation for a Rare Disease of Langerhans Cell Histiocytosis Involving Thyroid

• Published in: Medicine (Baltimore) 2015-11, Vol.94 (44), p.e1891-e1891
• Main Authors: Cai, Ye-Feng, Wang, Qing-Xuan, Ni, Chun-Jue, Dong, Si-Yang, Lv, Lin, Li, Quan, Chen, En-Dong, Zhang, Xiao-Hua
• Format: Article
• Language: English
• Subjects: Adult; Biopsy; Clinical Case Report; Diagnosis, Differential; Histiocytosis, Langerhans-Cell - complications; Histiocytosis, Langerhans-Cell - diagnosis; Humans; Male; Positron-Emission Tomography; Rare Diseases; Thyroid Diseases - complications; Thyroid Diseases - diagnosis; Thyroid Gland - diagnostic imaging; Thyroid Gland - pathology; Tomography, X-Ray Computed
• ISSN: 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000001891

Langerhans cell histiocytosis (LCH) involving the thyroid gland is extremely rare. Currently, the diagnosis and therapeutic evaluation for LCH involving thyroid is a challenge.We reported a rare case of LCH involving thyroid, presenting as painless thyroid goiters, and successfully performed positron emission tomography/computed tomography (PET/CT) to make an accurate diagnosis and therapeutic evaluation for LCH.Although the histology or cytology is the golden standard for the diagnosis of LCH involving thyroid, the PET/CT should be keep in mind when LCH involving thyroid with inconclusive cytologic results. During the treatment of LCH, PET/CT can be performed to assess the therapeutic effect and select the most effective and reliable treatment for LCH.