Cutaneous afferent activity in median and radial nerve fascicles: a microelectrode study

Cutaneous afferent activity was recorded in fascicles of the median and radial nerves of normal subjects using percutaneous microelectrodes. Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and...

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Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1975-09, Vol.38 (9), p.855-864
Main Authors: Burke, D, Mackenzie, R A, Skuse, N F, Lethlean, A K
Format: Article
Language:English
Subjects:
Adult
Electric Stimulation
Evoked Potentials
Humans
Median Nerve - physiology
Middle Aged
Nerve Fibers, Myelinated - physiology
Neurons, Afferent - physiology
Pain
Radial Nerve - physiology
Skin - innervation
Touch - physiology
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container_title Journal of neurology, neurosurgery and psychiatry
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creator Burke, D
Mackenzie, R A
Skuse, N F
Lethlean, A K
description Cutaneous afferent activity was recorded in fascicles of the median and radial nerves of normal subjects using percutaneous microelectrodes. Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and slow myelinated fibre activity but more intense levels were required to activate unmyelinated fibres. Correlation of the evoked potentials and the sensations reported by the subject suggested that fast myelinated fibres mediate tactile sensations. Pricking pain appeared with the activation of slow myelinated fibres. The only sensations induced by electrical stimuli were tactile or painful.
doi_str_mv 10.1136/jnnp.38.9.855
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subjects Adult
Electric Stimulation
Evoked Potentials
Humans
Median Nerve - physiology
Middle Aged
Nerve Fibers, Myelinated - physiology
Neurons, Afferent - physiology
Pain
Radial Nerve - physiology
Skin - innervation
Touch - physiology
title Cutaneous afferent activity in median and radial nerve fascicles: a microelectrode study
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