Human metapneumovirus infections in hematopoietic cell transplant recipients and hematologic malignancy patients: A systematic review

Highlights • First systematic review on hMPV infections in HM patients and HCT recipients. • hMPV incidence, risk factors, morbidity, and mortality were reviewed from all published studies. • Data on antiviral therapy, ongoing clinical trials and vaccine trials are also examined.

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Bibliographic Details
Published in:Cancer letters 2016-08, Vol.379 (1), p.100-106
Main Authors: Shah, Dimpy P, Shah, Pankil K, Azzi, Jacques M, El Chaer, Firas, Chemaly, Roy F
Format: Article
Language:English
Subjects:
Antiviral Agents - therapeutic use
Cancer
Fatalities
Hematologic Neoplasms - diagnosis
Hematologic Neoplasms - mortality
Hematologic Neoplasms - virology
Hematology, Oncology and Palliative Medicine
Hematopoietic Stem Cell Transplantation - adverse effects
Hematopoietic Stem Cell Transplantation - mortality
hMPV
Human metapneumovirus
Humans
Immunoglobulins, Intravenous - therapeutic use
Incidence
Leukemia
Lymphoma
Metapneumovirus - drug effects
Metapneumovirus - pathogenicity
Mortality
Parainfluenza virus
Paramyxoviridae Infections - diagnosis
Paramyxoviridae Infections - drug therapy
Paramyxoviridae Infections - mortality
Paramyxoviridae Infections - virology
Predictive Value of Tests
Prognosis
Respiratory syncytial virus
Respiratory Tract Infections - diagnosis
Respiratory Tract Infections - drug therapy
Respiratory Tract Infections - mortality
Respiratory Tract Infections - virology
Risk Factors
Stem cell transplantation
Studies
Systematic review
Viral infections
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Description
Summary:Highlights • First systematic review on hMPV infections in HM patients and HCT recipients. • hMPV incidence, risk factors, morbidity, and mortality were reviewed from all published studies. • Data on antiviral therapy, ongoing clinical trials and vaccine trials are also examined.
ISSN:0304-3835
1872-7980
DOI:10.1016/j.canlet.2016.05.035