Comparison of 3 T and 1.5 T for T2 magnetic resonance of tissue iron

T2* magnetic resonance of tissue iron concentration has improved the outcome of transfusion dependant anaemia patients. Clinical evaluation is performed at 1.5 T but scanners operating at 3 T are increasing in numbers. There is a paucity of data on the relative merits of iron quantification at 3 T v...

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Bibliographic Details
Published in:Journal of cardiovascular magnetic resonance 2016-07, Vol.18 (1), p.40-40, Article 40
Main Authors: Alam, Mohammed H, Auger, Dominique, McGill, Laura-Ann, Smith, Gillian C, He, Taigang, Izgi, Cemil, Baksi, A John, Wage, Rick, Drivas, Peter, Firmin, David N, Pennell, Dudley J
Format: Article
Language:English
Subjects:
Adult
Algorithms
Analysis
Anemia
Blood transfusion
Cardiomyopathies - diagnosis
Cardiomyopathies - metabolism
Care and treatment
Case-Control Studies
Chi-Square Distribution
Female
Hemosiderosis - diagnosis
Hemosiderosis - metabolism
Humans
Image Interpretation, Computer-Assisted
Iron - analysis
Linear Models
Liver - chemistry
Liver - diagnostic imaging
Liver Diseases - diagnosis
Liver Diseases - metabolism
Magnetic resonance imaging
Magnetic Resonance Imaging, Cine
Male
Middle Aged
Myocardium - chemistry
Nonlinear Dynamics
Observer Variation
Predictive Value of Tests
Prospective Studies
Reproducibility of Results
Young Adult
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Summary:T2* magnetic resonance of tissue iron concentration has improved the outcome of transfusion dependant anaemia patients. Clinical evaluation is performed at 1.5 T but scanners operating at 3 T are increasing in numbers. There is a paucity of data on the relative merits of iron quantification at 3 T vs 1.5 T. A total of 104 transfusion dependent anaemia patients and 20 normal volunteers were prospectively recruited to undergo cardiac and liver T2* assessment at both 1.5 T and 3 T. Intra-observer, inter-observer and inter-study reproducibility analysis were performed on 20 randomly selected patients for cardiac and liver T2*. Association between heart and liver T2* at 1.5 T and 3 T was non-linear with good fit (R (2) = 0.954, p 
ISSN:1097-6647
1532-429X
DOI:10.1186/s12968-016-0259-9