Early-onset glaucoma in Axenfeld–Rieger anomaly: long-term surgical results and visual outcome

Purpose To determine the long-term surgical and visual outcomes in Indian children with early-onset glaucoma associated with Axenfeld–Rieger anomaly (ARA). Methods This is a retrospective analysis of 44 eyes of 24 consecutive children with early-onset glaucoma (within 3 years of age) and ARA who und...

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Bibliographic Details
Published in:Eye (London) 2016-07, Vol.30 (7), p.936-942
Main Authors: Mandal, A K, Pehere, N
Format: Article
Language:English
Subjects:
692/1807/1482
692/699/3161/3164
692/700/1720
Anterior Eye Segment - abnormalities
Anterior Eye Segment - physiopathology
Child, Preschool
Clinical Study
Corneal Edema - physiopathology
Eye Abnormalities - complications
Eye Abnormalities - physiopathology
Female
Follow-Up Studies
Glaucoma
Glaucoma - etiology
Glaucoma - physiopathology
Glaucoma - surgery
Humans
Infant
Infant, Newborn
Intraocular Pressure - physiology
Laboratory Medicine
Male
Medicine
Medicine & Public Health
Ophthalmology
Pharmaceutical Sciences/Technology
Refractive Errors - physiopathology
Retrospective Studies
Surgery
Surgical Oncology
Trabeculectomy
Visual Acuity - physiology
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Summary:Purpose To determine the long-term surgical and visual outcomes in Indian children with early-onset glaucoma associated with Axenfeld–Rieger anomaly (ARA). Methods This is a retrospective analysis of 44 eyes of 24 consecutive children with early-onset glaucoma (within 3 years of age) and ARA who underwent glaucoma surgery over a 20-year period (1991–2010) by a single surgeon. Main outcome measures were pre- and postoperative intraocular pressures (IOPs), corneal clarity, visual acuities (VAs), refractive errors, success rate, time of surgical failure, and complications. Results The series consisted of 38 primary combined trabeculotomy–trabeculectomy (CTT) and 6 primary trabeculectomy procedures (Schlemm’s canal could not be identified in these eyes). There was a statistically significant reduction in IOP postoperatively (27.07±4.88 vs 14.88±3.62 mm Hg; P
ISSN:0950-222X
1476-5454
DOI:10.1038/eye.2016.66