Stem cell procedures in arthroscopic surgery

The stem cell as the building block necessary for tissue reparation and homeostasis plays a major role in regenerative medicine. Their unique property of being pluripotent, able to control immune process and even secrete a whole army of anabolic mediators, draws interest. While new arthroscopic proc...

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Bibliographic Details
Published in:European journal of medical research 2016-07, Vol.21 (1), p.29-29, Article 29
Main Authors: Dyrna, Felix, Herbst, Elmar, Hoberman, Alexander, Imhoff, Andreas B, Schmitt, Andreas
Format: Article
Language:English
Subjects:
Analysis
Animals
Arthroscopy
Arthroscopy - methods
Endoscopic surgery
Health aspects
Humans
Joints
Mesenchymal Stem Cell Transplantation
Mesenchymal Stromal Cells - cytology
Mesenchymal Stromal Cells - immunology
Methods
Review
Stem cells
Transplantation
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Summary:The stem cell as the building block necessary for tissue reparation and homeostasis plays a major role in regenerative medicine. Their unique property of being pluripotent, able to control immune process and even secrete a whole army of anabolic mediators, draws interest. While new arthroscopic procedures and techniques involving stem cells have been established over the last decade with improved outcomes, failures and dissatisfaction still occur. Therefore, there is increasing interest in ways to improve the healing response. MSCs are particularly promising for this task given their regenerative potential. While methods of isolating those cells are no longer poses a challenge, the best way of application is not clear. Several experiments in the realm of basic science and animal models have recently been published, addressing this issue, yet the application in clinical practice has lagged. This review provides an overview addressing the current standing of MSCs in the field of arthroscopic surgery.
ISSN:2047-783X
0949-2321
2047-783X
DOI:10.1186/s40001-016-0224-y