Clinical Pattern of Early-Onset Inflammatory Bowel Disease in Saudi Arabia: A Multicenter National Study

The objectives of this multicenter national study were to compare the clinical phenotype of early-onset inflammatory bowel disease (IBD) (EO-IBD) with IBD in older children and to examine whether there is any variability in consanguinity rate and familial aggregation in EO-IBD compared with later on...

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Bibliographic Details
Published in:Inflammatory bowel diseases 2016-08, Vol.22 (8), p.1961-1970
Main Authors: Al-Hussaini, Abdulrahman, El Mouzan, Mohammad, Hasosah, Mohammed, Al-Mehaidib, Ali, ALSaleem, Khalid, Saadah, Omar I, Al-Edreesi, Mohammed
Format: Article
Language:English
Subjects:
Abdominal Pain - etiology
Adolescent
Age of Onset
Child
Child Development
Child, Preschool
Colitis, Ulcerative - complications
Colitis, Ulcerative - diagnosis
Colitis, Ulcerative - genetics
Colitis, Ulcerative - pathology
Colon - pathology
Consanguinity
Crohn Disease - complications
Crohn Disease - diagnosis
Crohn Disease - pathology
Developmental Disabilities - etiology
Diarrhea - etiology
Female
Humans
Ileum - pathology
Infant
Infant, Newborn
Male
Original
Phenotype
Retrospective Studies
Saudi Arabia
Sex Factors
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Summary:The objectives of this multicenter national study were to compare the clinical phenotype of early-onset inflammatory bowel disease (IBD) (EO-IBD) with IBD in older children and to examine whether there is any variability in consanguinity rate and familial aggregation in EO-IBD compared with later onset IBD. A retrospective analysis was performed on children aged 0 to 14 years with IBD in 17 centers located in geographically distinct regions in Saudi Arabia, from 2003 to 2012. Data of patients with EO-IBD (0 to
ISSN:1078-0998
1536-4844
DOI:10.1097/MIB.0000000000000796