Histopathological and microanalytical study of zirconium dioxide and barium sulphate in bone cement

AIMS: To report the appearances of zirconium dioxide and barium sulphate in interface membranes, synovium, and other tissues around joint prostheses. METHODS: Histological sections from 23 specimens were reviewed by light microscopy and polarisation. Scanning electron microscopy and x ray microanaly...

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Bibliographic Details
Published in:Journal of clinical pathology 1992-11, Vol.45 (11), p.984-989
Main Authors: Keen, C E, Philip, G, Brady, K, Spencer, J D, Levison, D A
Format: Article
Language:English
Subjects:
Adult
Aged
Barium Sulfate - analysis
Biological and medical sciences
Bone Cements - chemistry
Electron Probe Microanalysis
Hip Prosthesis
Humans
Knee Prosthesis
Medical sciences
Microscopy, Electron, Scanning
Middle Aged
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Zirconium - analysis
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Summary:AIMS: To report the appearances of zirconium dioxide and barium sulphate in interface membranes, synovium, and other tissues around joint prostheses. METHODS: Histological sections from 23 specimens were reviewed by light microscopy and polarisation. Scanning electron microscopy and x ray microanalysis were performed on routinely processed paraffin wax sections. RESULTS: Polyethylene, metals, and polymethylmethacrylate cement debris were easily recognisable. Almost all the cement remnants contained either zirconium dioxide or barium sulphate, confirmed by microanalysis. The contrast media had characteristic light microscopic appearances. Zirconium was identified in macrophages away from cement remnants. CONCLUSION: The presence of radiographic contrast media in tissues around prosthetic joints is common but not widely recognised.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.45.11.984