Pregnancy and ketoacidosis: Is pancreatitis a missing link?

Non-diabetic ketoacidosis is increasingly recognised in pregnancy, particularly during the third trimester, and is usually associated with vomiting. In many cases, the cause of the vomiting is not identified and resolves rapidly, alongside the metabolic abnormalities, following delivery. Here, we re...

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Bibliographic Details
Published in:Obstetric Medicine 2016-06, Vol.9 (2), p.60-63
Main Authors: Frise, Charlotte J, Ashcroft, Anna, Jones, Bryony A, Mackillop, Lucy
Format: Article
Language:English
Subjects:
Diabetes
Metabolism
Pancreatitis
Pregnancy
Review
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Summary:Non-diabetic ketoacidosis is increasingly recognised in pregnancy, particularly during the third trimester, and is usually associated with vomiting. In many cases, the cause of the vomiting is not identified and resolves rapidly, alongside the metabolic abnormalities, following delivery. Here, we report three cases in which pancreatitis was identified as an underlying cause of the gastrointestinal symptoms. To our knowledge, these are the first reports of pancreatitis precipitating non-diabetic ketoacidosis in pregnancy. This case series highlights the importance of searching for a precipitant for non-diabetic ketoacidosis in pregnancy, rather than focusing solely on management of the resulting metabolic abnormalities.
ISSN:1753-495X
1753-4968
DOI:10.1177/1753495X15612330