Analysis of repeated 24-core saturation prostate biopsy: Inverse association between asymptomatic histological inflammation and prostate cancer detection

Saturation prostate biopsy protocols have been developed to improve the prostate cancer (PCa) detection rate, particularly in the setting of repeat biopsies. The present study attempted to clarify the association between PCa detection and various risk factors in repeat saturation biopsies. A retrosp...

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Bibliographic Details
Published in:Oncology letters 2016-08, Vol.12 (2), p.1132-1138
Main Authors: Kato, Tomonori, Komiya, Akira, Morii, Akihiro, Iida, Hiroaki, Ito, Takatoshi, Fuse, Hideki
Format: Article
Language:English
Subjects:
Antigens
Biopsy
Care and treatment
Catheters
Diagnosis
histological inflammation
Inflammation
Measurement
Methods
Multivariate analysis
NMR
Nuclear magnetic resonance
Oncology
Patients
Prostate cancer
Prostate-specific antigen
repeat biopsy
saturation biopsy
Standard deviation
transperineal biopsy
Ultrasonic imaging
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Summary:Saturation prostate biopsy protocols have been developed to improve the prostate cancer (PCa) detection rate, particularly in the setting of repeat biopsies. The present study attempted to clarify the association between PCa detection and various risk factors in repeat saturation biopsies. A retrospective analysis was conducted on 78 Japanese patients for whom findings had caused suspicion of PCa despite previous negative prostate biopsies, and who consecutively underwent a 24-core transperineal repeat biopsy at Toyama University Hospital (Toyama, Japan). PCa was confirmed histologically in 16 of the 78 patients (20.5%). A univariate analysis revealed that the prostate-specific antigen (PSA) level at repeat biopsy was higher (P
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2016.4693