Interplay between Tumor Microenvironment and Cancer Cells

Kallesh D. Jayappa 1 and Ramesh C. Kovi 2 and Sumanta Chatterjee 3 1, Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA 2, Experimental Pathology Laboratories Inc. and National Toxicology Program, NIEHS, Research Triangle Park, NC 2770...

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Bibliographic Details
Published in:BioMed research international 2016-01, Vol.2016, p.4650498-2
Main Authors: Jayappa, Kallesh D., Kovi, Ramesh C., Chatterjee, Sumanta
Format: Article
Language:English
Subjects:
Biomedical research
Cancer
Cancer therapies
Care and treatment
Cell Proliferation - genetics
Cell Survival - genetics
Gender differences
Humans
Immunology
Liver cancer
Metastasis
Monocarboxylic Acid Transporters - genetics
Monocarboxylic Acid Transporters - metabolism
Neoplasm Metastasis
Neoplasms - genetics
Neoplasms - pathology
Oncology, Experimental
Potassium
Studies
Tumor Microenvironment - genetics
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Summary:Kallesh D. Jayappa 1 and Ramesh C. Kovi 2 and Sumanta Chatterjee 3 1, Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA 2, Experimental Pathology Laboratories Inc. and National Toxicology Program, NIEHS, Research Triangle Park, NC 27709, USA 3, Department of Immunology and Regenerative Medicine Program, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada Received 14 April 2016; Accepted 18 April 2016; 12 July 2016 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Interestingly, the paper by Z. Xia et al. showed the overexpression of potassium ions in liver cancer cells by the treatment with potassium ions that trigger cancer cell apoptosis, providing convincing evidence in favor of tumor suppression function of potassium ion channels in liver cancer.
ISSN:2314-6133
2314-6141
DOI:10.1155/2016/4650498