Loading…

Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review

Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cra...

Full description

Saved in:
Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2016-02, Vol.8 (2), p.e510
Main Authors: Galgano, Michael A, Padalino, David J, Fullmer, Joseph, Krishnamurthy, Satish
Format: Article
Language:English
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page
container_issue 2
container_start_page e510
container_title Curēus (Palo Alto, CA)
container_volume 8
creator Galgano, Michael A
Padalino, David J
Fullmer, Joseph
Krishnamurthy, Satish
description Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation.
doi_str_mv 10.7759/cureus.510
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4969148</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1953385122</sourcerecordid><originalsourceid>FETCH-LOGICAL-c262t-b2b30f42129ee9493054c97ac6f5f2428a5f11b724af40b26bfc8fd97aab2a783</originalsourceid><addsrcrecordid>eNpVkUtLAzEUhYMoVmo3_gAJuBOmJpnMy4UwFLVCwQe6DplM0qbMTGqSqfTfm9Ja6iqH3I9zD_cAcIXROMuS4k70VvZunGB0Ai4ITvMoxzk9PdIDMHJuiRDCKCMoQ-dgQDJaxDklF-B9Kltj7YLPtYBvujFi44MqnbdbaVruoO5gWfeNd_ewhBPuJPyQK2M95F0NZ9pLy31IEX7XWv5cgjPFGydH-3cIvp4ePyfTaPb6_DIpZ5EgKfFRRaoYKUowKaQsQhyUUFFkXKQqUYSSnCcK4yojlCuKKpJWSuSqDgSvCM_yeAgedr6rvmplLWTnLW_YyuqW2w0zXLP_k04v2NysGS3SAtOtwc3ewJrvXjrPlqa3XcjMcJHEcZ5gQgJ1u6OENc5ZqQ4bMGLbBtiuARYaCPD1caYD-nfv-BecpoN0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1953385122</pqid></control><display><type>article</type><title>Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Galgano, Michael A ; Padalino, David J ; Fullmer, Joseph ; Krishnamurthy, Satish</creator><creatorcontrib>Galgano, Michael A ; Padalino, David J ; Fullmer, Joseph ; Krishnamurthy, Satish</creatorcontrib><description>Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.510</identifier><identifier>PMID: 27493842</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Case reports ; Neurosurgery ; Oncology</subject><ispartof>Curēus (Palo Alto, CA), 2016-02, Vol.8 (2), p.e510</ispartof><rights>Copyright © 2016, Galgano et al. This work is licensed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2016, Galgano et al. 2016 Galgano et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1953385122/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1953385122?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,25734,27905,27906,36993,44571,53772,53774,74875</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27493842$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Galgano, Michael A</creatorcontrib><creatorcontrib>Padalino, David J</creatorcontrib><creatorcontrib>Fullmer, Joseph</creatorcontrib><creatorcontrib>Krishnamurthy, Satish</creatorcontrib><title>Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review</title><title>Curēus (Palo Alto, CA)</title><addtitle>Cureus</addtitle><description>Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation.</description><subject>Case reports</subject><subject>Neurosurgery</subject><subject>Oncology</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNpVkUtLAzEUhYMoVmo3_gAJuBOmJpnMy4UwFLVCwQe6DplM0qbMTGqSqfTfm9Ja6iqH3I9zD_cAcIXROMuS4k70VvZunGB0Ai4ITvMoxzk9PdIDMHJuiRDCKCMoQ-dgQDJaxDklF-B9Kltj7YLPtYBvujFi44MqnbdbaVruoO5gWfeNd_ewhBPuJPyQK2M95F0NZ9pLy31IEX7XWv5cgjPFGydH-3cIvp4ePyfTaPb6_DIpZ5EgKfFRRaoYKUowKaQsQhyUUFFkXKQqUYSSnCcK4yojlCuKKpJWSuSqDgSvCM_yeAgedr6rvmplLWTnLW_YyuqW2w0zXLP_k04v2NysGS3SAtOtwc3ewJrvXjrPlqa3XcjMcJHEcZ5gQgJ1u6OENc5ZqQ4bMGLbBtiuARYaCPD1caYD-nfv-BecpoN0</recordid><startdate>20160224</startdate><enddate>20160224</enddate><creator>Galgano, Michael A</creator><creator>Padalino, David J</creator><creator>Fullmer, Joseph</creator><creator>Krishnamurthy, Satish</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20160224</creationdate><title>Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review</title><author>Galgano, Michael A ; Padalino, David J ; Fullmer, Joseph ; Krishnamurthy, Satish</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c262t-b2b30f42129ee9493054c97ac6f5f2428a5f11b724af40b26bfc8fd97aab2a783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Case reports</topic><topic>Neurosurgery</topic><topic>Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Galgano, Michael A</creatorcontrib><creatorcontrib>Padalino, David J</creatorcontrib><creatorcontrib>Fullmer, Joseph</creatorcontrib><creatorcontrib>Krishnamurthy, Satish</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Galgano, Michael A</au><au>Padalino, David J</au><au>Fullmer, Joseph</au><au>Krishnamurthy, Satish</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2016-02-24</date><risdate>2016</risdate><volume>8</volume><issue>2</issue><spage>e510</spage><pages>e510-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>27493842</pmid><doi>10.7759/cureus.510</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2168-8184
ispartof Curēus (Palo Alto, CA), 2016-02, Vol.8 (2), p.e510
issn 2168-8184
2168-8184
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4969148
source Publicly Available Content Database; PubMed Central
subjects Case reports
Neurosurgery
Oncology
title Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T17%3A51%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hemorrhagic%20Pilocytic%20Astrocytomas%20in%20Adults:%20A%20Case%20Report%20and%20Literature%20Review&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Galgano,%20Michael%20A&rft.date=2016-02-24&rft.volume=8&rft.issue=2&rft.spage=e510&rft.pages=e510-&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.510&rft_dat=%3Cproquest_pubme%3E1953385122%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c262t-b2b30f42129ee9493054c97ac6f5f2428a5f11b724af40b26bfc8fd97aab2a783%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1953385122&rft_id=info:pmid/27493842&rfr_iscdi=true