Strongyloides stercoralis hyperinfection in an HIV positive patient

A 25 year old British man of previous good health presented with persistent generalised lymphadenopathy and was found to be human immunodeficiency virus (HIV) antibody positive. Three years later after weight loss and loose stools Strongyloides stercoralis was identified in the latter and successful...

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Bibliographic Details
Published in:Journal of clinical pathology 1991-04, Vol.44 (4), p.346-348
Main Authors: Harcourt-Webster, J N, Scaravilli, F, Darwish, A H
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Biological and medical sciences
HIV Seropositivity - complications
human immunodeficiency virus
Humans
Infectious diseases
Intestine, Small - pathology
Male
Medical sciences
Opportunistic Infections - complications
Opportunistic Infections - pathology
Parasitic diseases
Strongyloidiasis - complications
Strongyloidiasis - pathology
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Summary:A 25 year old British man of previous good health presented with persistent generalised lymphadenopathy and was found to be human immunodeficiency virus (HIV) antibody positive. Three years later after weight loss and loose stools Strongyloides stercoralis was identified in the latter and successfully treated with thiabendazole. Shortly afterwards, a further episode again responded rapidly, but was swiftly followed by a final and fatal illness with severe debility and metabolic imbalance unresponsive to all treatment. Necropsy showed widespread and heavy strongyloidiasis with pulmonary haemorrhage, bronchopneumonia, and meningitis.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.44.4.346