Disseminated cryptococcosis presenting as mediastinal and hilar lymphadenopathy in an immunocompetent patient

We herein report a rare case of disseminated cryptococcosis presenting as mediastinal and hilar lymphadenopathy in a young immunocompetent man. A previously healthy 26‐year‐old man presented with persistent headache and nonproductive cough. Chest computed tomography indicated mediastinal and hilar l...

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Bibliographic Details
Published in:Respirology case reports 2016-07, Vol.4 (4), p.e00167-n/a
Main Authors: Murakami, Yasushi, Oki, Masahide, Saka, Hideo, Kajikawa, Shigehisa, Murakami, Ayuka, Ishida, Akane
Format: Article
Language:English
Subjects:
Antigens
Blood
Case Report
Case Reports
Disseminated cryptococcosis
EBUS‐TBNA
Fungal infections
HIV
Human immunodeficiency virus
Immunocompetence
immunocompetent patient
Infections
Lymphatic system
mediastinal lymphadenopathy
Meningitis
Microorganisms
Organisms
Patients
Tomography
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Summary:We herein report a rare case of disseminated cryptococcosis presenting as mediastinal and hilar lymphadenopathy in a young immunocompetent man. A previously healthy 26‐year‐old man presented with persistent headache and nonproductive cough. Chest computed tomography indicated mediastinal and hilar lymphadenopathy. Cryptococcal lymphadenitis and meningitis was confirmed by endobronchial ultrasound‐guided transbronchial needle aspiration and central spinal fluid examination, respectively. He received liposomal amphotericin B and flucytosine followed by fluconazole and finally improved. We encountered a rare case of disseminated cryptococcosis presenting as hilar and mediastinal lymphadenopathy in a young immunocompetent man. Chest X‐Ray showed massive lymphadenopathy mimicking thoracic malignancies.
ISSN:2051-3380
2051-3380
DOI:10.1002/rcr2.167