Complications of Treatment in Youth with HIV

While combination antiretroviral therapy allows HIV-infected patients to have life expectancies similar to that of the general population, it may also contribute to the development of co-morbidities, such as cardiovascular disease and osteoporosis. Such complications could compromise long-term quali...

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Bibliographic Details
Published in:Current HIV/AIDS reports 2016-08, Vol.13 (4), p.226-233
Main Authors: Eckard, Allison Ross, Fowler, Sandra L., Haston, Julia C., Dixon, Terry C.
Format: Article
Language:English
Subjects:
Adolescent
Anti-HIV Agents - adverse effects
Anti-HIV Agents - therapeutic use
Antiretroviral Therapy, Highly Active
Cardiovascular Diseases - epidemiology
Comorbidity
Complications of Antiretroviral Therapy (G McComsey
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - epidemiology
Humans
Medicine
Medicine & Public Health
Osteoporosis - epidemiology
Quality of Life
Section Editor
Topical Collection on Complications of Antiretroviral Therapy
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Summary:While combination antiretroviral therapy allows HIV-infected patients to have life expectancies similar to that of the general population, it may also contribute to the development of co-morbidities, such as cardiovascular disease and osteoporosis. Such complications could compromise long-term quality of life, especially in HIV-infected youth whose lifetime cumulative exposure to antiretrovirals is likely to be many decades. Recent studies continue to demonstrate abnormalities associated with antiretroviral therapy, although clinical manifestations are rare in this younger population, especially with modern antiretrovirals. The purpose of this paper is to review the most recent literature on complications of treatment in youth with HIV.
ISSN:1548-3568
1548-3576
DOI:10.1007/s11904-016-0320-1