A quantitative study of alpha-naphthyl acetate esterase-positive cells in non-Hodgkin's lymphomas and reactive lymph nodes

The numbers of alpha-naphthyl acetate esterase (ANAE)-containing cells (other than T lymphocytes) in non-Hodgkin's lymphomas (NHL) and reactive lymph nodes have been counted, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyzer. Twenty specimens of NHL and ten reactive node...

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Bibliographic Details
Published in:Journal of clinical pathology 1982-10, Vol.35 (10), p.1066-1068
Main Authors: Crocker, J, Jones, E L, Curran, R C
Format: Article
Language:English
Subjects:
Carboxylic Ester Hydrolases - metabolism
Cell Count
Humans
Lymph Nodes - enzymology
Lymph Nodes - pathology
Lymphoma - enzymology
Lymphoma - pathology
Naphthol AS D Esterase - metabolism
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Summary:The numbers of alpha-naphthyl acetate esterase (ANAE)-containing cells (other than T lymphocytes) in non-Hodgkin's lymphomas (NHL) and reactive lymph nodes have been counted, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyzer. Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). The number of ANAE-positive cells (1.4-3.2%) in reactive lymph nodes was similar to that in low-grade NHL nodes.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.35.10.1066