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A quantitative study of alpha-naphthyl acetate esterase-positive cells in non-Hodgkin's lymphomas and reactive lymph nodes
The numbers of alpha-naphthyl acetate esterase (ANAE)-containing cells (other than T lymphocytes) in non-Hodgkin's lymphomas (NHL) and reactive lymph nodes have been counted, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyzer. Twenty specimens of NHL and ten reactive node...
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Published in: | Journal of clinical pathology 1982-10, Vol.35 (10), p.1066-1068 |
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container_title | Journal of clinical pathology |
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creator | Crocker, J Jones, E L Curran, R C |
description | The numbers of alpha-naphthyl acetate esterase (ANAE)-containing cells (other than T lymphocytes) in non-Hodgkin's lymphomas (NHL) and reactive lymph nodes have been counted, using the Reichert-Jung (Kontron) MOP-AMO3 user-controlled image analyzer. Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). The number of ANAE-positive cells (1.4-3.2%) in reactive lymph nodes was similar to that in low-grade NHL nodes. |
doi_str_mv | 10.1136/jcp.35.10.1066 |
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Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). 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Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). The number of ANAE-positive cells (1.4-3.2%) in reactive lymph nodes was similar to that in low-grade NHL nodes.</description><subject>Carboxylic Ester Hydrolases - metabolism</subject><subject>Cell Count</subject><subject>Humans</subject><subject>Lymph Nodes - enzymology</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphoma - enzymology</subject><subject>Lymphoma - pathology</subject><subject>Naphthol AS D Esterase - metabolism</subject><issn>0021-9746</issn><issn>1472-4146</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1982</creationdate><recordtype>article</recordtype><recordid>eNqFkUtv1DAUhS0EKtPClh2SJSQQCw927LGTRRfViHYQI1jw2FpOctN4mtipnVRMfz2eh0bAho0t3_Md-14fhF4xOmeMyw-bapjzxXx3pFI-QTMmVEYEE_IpmlGaMVIoIZ-j8xg3lDKuGD9DZ2mlgqkZerzC95Nxox3NaB8Ax3Gqt9g32HRDa4gzQzu22w6bChIBGOIIwUQgg49276ig6yK2DjvvyMrXt3fWvYu42_ZD63sTsXE1DmCqPb0vJ7SG-AI9a0wX4eVxv0A_rj9-X67I-uvNp-XVmpQiFyMRkFdNKYELSRtVNpynMpVZLgopVFkLlSuxUCpTNM9qXrCmKcoKQMqiLCgYfoEuD_cOU9lDXYEbg-n0EGxvwlZ7Y_XfirOtvvUPWhQqz0Xyvz36g7-f0gfo3sbd1MaBn6JWIhNSZjSBb_4BN34KLs2mmVI0YSrjiZofqCr4GAM0p04Y1btIdYpU88X-mCJNhtd_9n_CjxkmnRx0m7L5dZJNuNNScbXQX34u9bXky5tvn9d6lfj3B77sN_97-zdiDrse</recordid><startdate>19821001</startdate><enddate>19821001</enddate><creator>Crocker, J</creator><creator>Jones, E L</creator><creator>Curran, R C</creator><general>BMJ Publishing Group Ltd and Association of Clinical Pathologists</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19821001</creationdate><title>A quantitative study of alpha-naphthyl acetate esterase-positive cells in non-Hodgkin's lymphomas and reactive lymph nodes</title><author>Crocker, J ; 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Twenty specimens of NHL and ten reactive nodes were examined. Cells were demonstrated by their content of acid alpha-naphthyl acetate esterase (ANAE) in fixed frozen sections. It was found that lymphomas of high-grade malignancy contained much larger numbers of ANAE-positive cells (10.8-20.5%) than those of low-grade malignancy (1.4-4.1%). The number of ANAE-positive cells (1.4-3.2%) in reactive lymph nodes was similar to that in low-grade NHL nodes.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and Association of Clinical Pathologists</pub><pmid>7130417</pmid><doi>10.1136/jcp.35.10.1066</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Carboxylic Ester Hydrolases - metabolism Cell Count Humans Lymph Nodes - enzymology Lymph Nodes - pathology Lymphoma - enzymology Lymphoma - pathology Naphthol AS D Esterase - metabolism |
title | A quantitative study of alpha-naphthyl acetate esterase-positive cells in non-Hodgkin's lymphomas and reactive lymph nodes |
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