Origin, Methods, and Evolution of the Three Nurses' Health Studies

We have summarized the evolution of the Nurses' Health Study (NHS), a prospective cohort study of 121 700 married registered nurses launched in 1976; NHS II, which began in 1989 and enrolled 116 430 nurses; and NHS3, which began in 2010 and has ongoing enrollment. Over 40 years, these studies h...

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Bibliographic Details
Published in:American journal of public health (1971) 2016-09, Vol.106 (9), p.1573-1581
Main Authors: Bao, Ying, Bertoia, Monica L, Lenart, Elizabeth B, Stampfer, Meir J, Willett, Walter C, Speizer, Frank E, Chavarro, Jorge E
Format: Article
Language:English
Subjects:
Adult
Aging
AJPH Methods
Birth Control
Cancer
Child development
Data collection
Data management
Demography
Enrollments
Epidemiologic Studies
Epidemiology
Exercise
Female
Health care
Health risk assessment
History
Humans
Interdisciplinary research
Lifestyles
Longitudinal Studies
Medical research
Middle Aged
Nurses
Obesity/Overweight/Underweight
Outdoor air quality
Pilot projects
Pregnancy
Prospective Studies
Public health
Questionnaires
Research Design
Research projects
Risk factors
Socioeconomic factors
Studies
Surveys and Questionnaires
United States
Women's Health
Womens health
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Summary:We have summarized the evolution of the Nurses' Health Study (NHS), a prospective cohort study of 121 700 married registered nurses launched in 1976; NHS II, which began in 1989 and enrolled 116 430 nurses; and NHS3, which began in 2010 and has ongoing enrollment. Over 40 years, these studies have generated long-term, multidimensional data, including lifestyle- and health-related information across the life course and an extensive repository of various biological specimens. We have described the questionnaire data collection, disease follow-up methods, biorepository resources, and data management and statistical procedures. Through integrative analyses, these studies have sustained a high level of scientific productivity and substantially influenced public health recommendations. We have highlighted recent interdisciplinary research projects and discussed future directions for collaboration and innovation.
ISSN:0090-0036
1541-0048
DOI:10.2105/ajph.2016.303338