LassoProt: server to analyze biopolymers with lassos

The LassoProt server, http://lassoprot.cent.uw.edu.pl/, enables analysis of biopolymers with entangled configurations called lassos. The server offers various ways of visualizing lasso configurations, as well as their time trajectories, with all the results and plots downloadable. Broad spectrum of...

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Bibliographic Details
Published in:Nucleic acids research 2016-07, Vol.44 (W1), p.W383-W389
Main Authors: Dabrowski-Tumanski, Pawel, Niemyska, Wanda, Pasznik, Pawel, Sulkowska, Joanna I
Format: Article
Language:English
Subjects:
Biopolymers - chemistry
Databases, Protein - standards
Internet
Models, Molecular
Proteins - chemistry
Proteins - metabolism
Reproducibility of Results
Software - standards
Web Server issue
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Summary:The LassoProt server, http://lassoprot.cent.uw.edu.pl/, enables analysis of biopolymers with entangled configurations called lassos. The server offers various ways of visualizing lasso configurations, as well as their time trajectories, with all the results and plots downloadable. Broad spectrum of applications makes LassoProt a useful tool for biologists, biophysicists, chemists, polymer physicists and mathematicians. The server and our methods have been validated on the whole PDB, and the results constitute the database of proteins with complex lassos, supported with basic biological data. This database can serve as a source of information about protein geometry and entanglement-function correlations, as a reference set in protein modeling, and for many other purposes.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/gkw308