Osteoradionecrosis in patients with salivary gland malignancies

Highlights • Risk of ORN after radiotherapy for salivary gland malignancy was 4% (95% CI: 1.6–8.2%). • ORN only occurred in patients treated with primary disease in the major glands or minor glands arising in the oral cavity. • Many cases of ORN developed after traumatic injury to the bone.

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Bibliographic Details
Published in:Oral oncology 2016-06, Vol.57, p.1-5
Main Authors: Tucker, J. Rhet, Xu, Li, Sturgis, Erich M, Mohamed, Abdallah S.R, Hofstede, Theresa M, Chambers, Mark S, Lai, Stephen Y, Fuller, Clifton David, Beadle, Beth, Gunn, G. Brandon, Hutcheson, Katherine A
Format: Article
Language:English
Subjects:
Bone Neoplasms - therapy
Carcinoma, Squamous Cell
Female
Hematology, Oncology and Palliative Medicine
Humans
Hyperbaric oxygen
Male
Middle Aged
Osteoradionecrosis
Osteoradionecrosis - therapy
Otolaryngology
Radiation therapy
Retrospective Studies
Salivary gland neoplasm
Salivary Gland Neoplasms - radiotherapy
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Summary:Highlights • Risk of ORN after radiotherapy for salivary gland malignancy was 4% (95% CI: 1.6–8.2%). • ORN only occurred in patients treated with primary disease in the major glands or minor glands arising in the oral cavity. • Many cases of ORN developed after traumatic injury to the bone.
ISSN:1368-8375
1879-0593
DOI:10.1016/j.oraloncology.2016.03.006