Prevalence and clinical aspects of CMV congenital Infection in a low-income population

CMV is the most common cause of congenital infection in the whole world (0.2 to 2.2 %). That infection may be symptomatic or asymptomatic at birth and, although asymptomatic cases at birth are more common, some children may develop late sequelae, and require medical intervention. This study aimed to...

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Bibliographic Details
Published in:Virology journal 2016-08, Vol.13 (1), p.148-148, Article 148
Main Authors: Marin, Lauro Juliano, Santos de Carvalho Cardoso, Emanuelle, Bispo Sousa, Sandra Mara, Debortoli de Carvalho, Luciana, Marques Filho, Marcílio F, Raiol, Mônica Regina, Gadelha, Sandra Rocha
Format: Article
Language:English
Subjects:
Adolescent
Analysis
Brazil - epidemiology
Child
Child, Preschool
Cytomegalovirus - genetics
Cytomegalovirus - isolation & purification
Cytomegalovirus - physiology
Cytomegalovirus infections
Cytomegalovirus Infections - congenital
Cytomegalovirus Infections - economics
Cytomegalovirus Infections - epidemiology
Cytomegalovirus Infections - virology
Development and progression
Disease transmission
Female
Humans
Infant
Influence
Male
Poverty
Prevalence
Rural Population - statistics & numerical data
Social economics
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Summary:CMV is the most common cause of congenital infection in the whole world (0.2 to 2.2 %). That infection may be symptomatic or asymptomatic at birth and, although asymptomatic cases at birth are more common, some children may develop late sequelae, and require medical intervention. This study aimed to determine the prevalence of CMV congenital infections in children who were born in a public hospital in Ilhéus, Brazil, and to evaluate the clinical progression in infected newborns. CMV congenital infection was determined by detecting viral DNA through nested PCR. The viral DNA was detected in 25 newborns, showing a prevalence of 1.19 % (25/2100) of CMV congenital infection. In regards to the risk factors from mothers, only the variables: age of mothers (p = 0.003), number of children (p = 0.011), and use of medications (p 
ISSN:1743-422X
1743-422X
DOI:10.1186/s12985-016-0604-5