A Role of Ginseng and Its Constituents in the Treatment of Central Nervous System Disorders

Ginseng, a perennial plant belonging to the Panax genus of the Araliaceae family, has been used in China, Korea, and Japan as a traditional herbal medicine for thousands of years. Ginseng is recorded to have exhibited a wide variety of beneficial pharmacological effects and has become a popular and...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2016-01, Vol.2016 (2016), p.1-7
Main Authors: Inui, Akio, Asakawa, Akihiro, Morinaga, Akinori, Amitani, Marie, Kapantow, Nova Hellen, Runtuwene, Joshua, Cheng, Kai-Chun, Kairupan, Timothy Sean, Rokot, Natasya Trivena, Amitani, Haruka
Format: Article
Language:English
Subjects:
Alzheimer's disease
Amyotrophic lateral sclerosis
Animal cognition
Araliaceae
B cells
Bioavailability
Central nervous system
Family medical history
Medicine, Botanic
Medicine, Herbal
Memory
Metabolites
Nervous system
Nervous system diseases
Neurons
Panax
Parkinson's disease
Phosphatase
Physiological aspects
Review
Rodents
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Summary:Ginseng, a perennial plant belonging to the Panax genus of the Araliaceae family, has been used in China, Korea, and Japan as a traditional herbal medicine for thousands of years. Ginseng is recorded to have exhibited a wide variety of beneficial pharmacological effects and has become a popular and worldwide known health supplement and drug. The protective effects of ginseng on central nervous system are discussed in this review. Ginseng species and ginsenosides and their intestinal metabolism and bioavailability are concisely introduced. The molecular mechanisms of the effects of ginseng on central nervous system, mainly focused on the neuroprotection properties of ginseng, memory, and learning enhanced properties, and the effects on neurodegenerative disorders are presented. Thus, ginseng and its constituents are of potential merits in the treatment of cerebral disorders.
ISSN:1741-427X
1741-4288
DOI:10.1155/2016/2614742