Measurement of liver function using hepatobiliary scintigraphy improves risk assessment in patients undergoing major liver resection

Abstract Background99m Tc-mebrofenin-hepatobiliary-scintigraphy (HBS) enables measurement of future remnant liver (FRL)-function and was implemented in our preoperative routine after calculation of the cut-off value for prediction of postoperative liver failure (LF). This study evaluates our results...

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Bibliographic Details
Published in:HPB (Oxford, England) England), 2016-09, Vol.18 (9), p.773-780
Main Authors: Cieslak, Kasia P, Bennink, Roelof J, de Graaf, Wilmar, van Lienden, Krijn P, Besselink, Marc G, Busch, Olivier R.C, Gouma, Dirk J, van Gulik, Thomas M
Format: Article
Language:English
Subjects:
Aged
Embolization, Therapeutic
Female
Gastroenterology and Hepatology
Hepatectomy - adverse effects
Humans
Imino Acids - administration & dosage
Liver - diagnostic imaging
Liver - physiopathology
Liver - surgery
Liver Failure - etiology
Liver Failure - prevention & control
Liver Function Tests
Male
Middle Aged
Organ Size
Organotechnetium Compounds - administration & dosage
Original
Portal Vein - diagnostic imaging
Predictive Value of Tests
Radiopharmaceuticals - administration & dosage
Retrospective Studies
Single Photon Emission Computed Tomography Computed Tomography
Treatment Outcome
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Summary:Abstract Background99m Tc-mebrofenin-hepatobiliary-scintigraphy (HBS) enables measurement of future remnant liver (FRL)-function and was implemented in our preoperative routine after calculation of the cut-off value for prediction of postoperative liver failure (LF). This study evaluates our results since the implementation of HBS. Additionally, CT-volumetric methods of FRL-assessment, standardized liver volumetry and FRL/body-weight ratio (FRL-BWR), were evaluated. Methods 163 patients who underwent major liver resection were included. Insufficient FRL-volume and/or FRL-function
ISSN:1365-182X
1477-2574
DOI:10.1016/j.hpb.2016.06.006