Does length of prostate biopsy cores have an impact on diagnosis of prostate cancer?

• Published in: Turkish journal of urology 2016-09, Vol.42 (3), p.130-133
• Main Authors: Ergün, Müslüm, Islamoglu, Ekrem, Yalçinkaya, Soner, Tokgöz, Hüsnü, Savas, Murat
• Format: Article
• Language: English
• Subjects: Urology; Urooncology
• ISSN: 2149-3235; 2149-3057; 2980-1478
• DOI: 10.5152/tud.2016.78700

Objective : To investigate whether core length is a significant biopsy parameter in the detection of prostate cancer. Material and methods : We retrospectively analyzed pathology reports of the specimens of 188 patients diagnosed with prostate cancer who had undergone initial transrectal ultrasound (TRUS) guided prostate biopsy, and compared biopsy core lengths of the patients with, and without prostate cancer. The biopsy specimens of prostate cancer patients were divided into 3 groups according to core length, and the data obtained were compared (Group 1; total core length 20 mm). Biopsy core lengths of the patients diagnosed as prostate cancer, and benign prostatic hyperplasia were compared, and a certain cut- off value for core length with optimal diagnostic sensitivity and specificity for prostate cancer was calculated. Results : Mean age, PSA and total length of cores were 65.08±7.41 years, 9.82±6.34 ng/mL and 11.2±0.2 mm, respectively. Assessment of biopsy core lengths showed that cores with cancer (n=993, median length 12.5 mm) were significantly longer than benign cores (n=1185, median length=11.3 mm) (p