Proteinuria can predict prognosis after liver transplantation

• Published in: BMC surgery 2016-09, Vol.16 (1), p.63-63, Article 63
• Main Authors: Pan, Heng-Chih, Chen, Ying-Jen, Lin, Jhe-Ping, Tsai, Ming-Jung, Jenq, Chang-Chyi, Lee, Wei-Chen, Tsai, Ming-Hung, Fan, Pei-Chun, Chang, Chih-Hsiang, Chang, Ming-Yang, Tian, Ya-Chung, Hung, Cheng-Chieh, Fang, Ji-Tseng, Yang, Chih-Wei, Chen, Yung-Chang
• Format: Article
• Language: English
• Subjects: Aged; Classification; Critical Care; Dopamine; End Stage Liver Disease - complications; End Stage Liver Disease - mortality; End Stage Liver Disease - surgery; Female; Health aspects; Hospital Mortality; Hospitalization; Humans; Intensive care; Intensive care units; Kidney diseases; Liver; Liver diseases; Liver Transplantation - adverse effects; Male; Management; Medical prognosis; Middle Aged; Mortality; Multivariate Analysis; Organ Dysfunction Scores; Patient outcomes; Patients; Predictive Value of Tests; Prognosis; Proteinuria; Proteinuria - etiology; Retrospective Studies; Transplantation; Transplants & implants; Urine
• ISSN: 1471-2482; 1471-2482
• DOI: 10.1186/s12893-016-0176-8

Proteinuria is a manifestation of renal dysfunction and it has been demonstrated to be a significant prognostic factor in various clinical situations. The study was designed to analyze prognosis of patients receiving liver transplantation as well as to determine predictive performance of perioperative proteinuria. We retrospectively reviewed data of patients who had received a liver transplant in a medical center between 2002 and 2010. Demographic information and clinical characteristic parameters were recorded on the day of intensive care unit admission before operation and on postoperative days 1, 7, and 14. Among a total of 323 patients, in-hospital mortality and 90-day mortality rates were 13.0 % (42/323) and 14.2 % (46/323), respectively. Patients with proteinuria on admission had higher rates of acute kidney injury (26.8 % vs. 8.8 %, p