Analyses on the misdiagnoses of 25 patients with unilateral optic nerve sheath meningioma

• Published in: International journal of ophthalmology 2016-09, Vol.9 (9), p.1315-1319
• Main Authors: Mao, Jun-Feng, Xia, Xiao-Bo, Tang, Xiang-Bo, Zhang, Xue-Yong, Wen, Dan
• Format: Article
• Language: English
• Subjects: Clinical Research
• ISSN: 2222-3959; 2227-4898
• DOI: 10.18240/ijo.2016.09.14

AIM：To investigate clinical features of optic nerve sheath meningioma（ONSM） that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS：Retrospective series study.Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan.2008 to Jan.2015 and the clinical records reviewed.RESULTS：Patients were misdiagnosed with acute papillitis most frequently（P=17）,immediately followed by optic atrophy（P=8）,ischemic optic neuropathy（P=5）,acute retrobulbar optic neuritis（P=5）,optic disc vasculitis（P =3）.For each patient,the minimum frequency of misdiagnoses was once and the maximum was 4 times.As for the lasting time of being misdiagnosed,the shortest was 1.5mo and the longest was 45 mo.Twentyone cases（84%） were once treated with glucocorticoids,and its side effects was found in seventeen patients.Twenty patients（80%） complained with varying degree of vision loss.When a definite diagnosis was made,sixteen cases（64%） showed slight exophthalmos and eighteen cases（72%） had the tubular ONSM.CONCLUSION：ONSM without loss obvious exophthalmos is easily misdiagnosed in clinic,and for most of these ONSMs are tubular.