Does FLT3 Mutation Impact Survival after Hematopoietic Cell Transplant for AML? A CIBMTR Analysis

1. FLT3 mutation status does not impact overall survival after allogeneic hematopoietic stem cell transplant. 2. Pre-emptive strategies to reduce relapse need to be investigated in FLT3 mutated patients to further improve post HCT outcomes.

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Bibliographic Details
Published in:Cancer 2016-06, Vol.122 (19), p.3005-3014
Main Authors: Deol, Abhinav, Sengsayadeth, Salyka, Ahn, Kwang Woo, Wang, Hai-Lin, Aljurf, Mahmoud, Antin, Joseph Harry, Battiwalla, Minoo, Bornhauser, Martin, Cahn, Jean-Yves, Camitta, Bruce, Chen, Yi-Bin, Cutler, Corey S., Gale, Robert Peter, Ganguly, Siddhartha, Hamadani, Mehdi, Inamoto, Yoshihiro, Jagasia, Madan, Kamble, Rammurti, Koreth, John, Lazarus, Hillard M., Liesveld, Jane, Litzow, Mark R., Marks, David I., Nishihori, Taiga, Olsson, Richard F., Reshef, Ran, Rowe, Jacob M., Saad, Ayman A., Sabloff, Mitchell, Schouten, Harry C., Shea, Thomas C., Soiffer, Robert J., Uy, Geoffrey L., Waller, Edmond K., Wiernik, Peter H., Wirk, Baldeep, Woolfrey, Ann E., Bunjes, Donald, Devine, Steven, de Lima, Marcos, Sandmaier, Brenda M., Weisdorf, Dan, Khoury, Hanna Jean, Saber, Wael
Format: Article
Language:English
Online Access:Get full text
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Summary:1. FLT3 mutation status does not impact overall survival after allogeneic hematopoietic stem cell transplant. 2. Pre-emptive strategies to reduce relapse need to be investigated in FLT3 mutated patients to further improve post HCT outcomes.
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.30140