Mean platelet volume provides beneficial diagnostic and prognostic information for patients with resectable gastric cancer

Gastric cancer is the fourth most frequent cancer and the second cause of cancer-related mortalities worldwide. Platelets play an important and multifaceted role in cancer progression. Elevated mean platelet volume (MPV) detected in peripheral blood has been identified in various types of cancer. In...

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Bibliographic Details
Published in:Oncology letters 2016-10, Vol.12 (4), p.2501-2506
Main Authors: Shen, Xiao-Ming, Xia, You-You, Lian, Lian, Zhou, Chong, Li, Xiang-Li, Han, Shu-Guang, Zheng, Yan, Gong, Fei-Ran, Tao, Min, Mao, Zhong-Qi, Li, Wei
Format: Article
Language:English
Subjects:
Age
Biomarkers
Blood platelets
Care and treatment
Committees
Development and progression
diagnosis
Gastric cancer
Gender
Identification and classification
Lymphatic system
mean platelet volume
Medical diagnosis
Medical prognosis
Metastasis
Oncology
prognosis
Risk factors
Statistical analysis
Stomach cancer
Surgery
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Summary:Gastric cancer is the fourth most frequent cancer and the second cause of cancer-related mortalities worldwide. Platelets play an important and multifaceted role in cancer progression. Elevated mean platelet volume (MPV) detected in peripheral blood has been identified in various types of cancer. In the present study, we investigated the application value of MPV in early diagnostic and prognostic prediction in patients with resectable gastric cancer. In total, 168 patients with resectable gastric cancer were included and separated into the gastric cancer and healthy control groups according to median pre-operatic MPV value (MPV low,
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2016.4913