Noninvasive diagnosis of vulnerable coronary plaque

Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease.For this reason,screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine.Necropsy studies have described histopathological...

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Bibliographic Details
Published in:World journal of cardiology 2016-09, Vol.8 (9), p.520-533
Main Authors: Pozo, Eduardo, Agudo-Quilez, Pilar, Rojas-González, Antonio, Alvarado, Teresa, Olivera, María José, Jiménez-Borreguero, Luis Jesús, Alfonso, Fernando
Format: Article
Language:English
Subjects:
Atherosclerosis
Vulnerable
computed
coronary
magnetic
plaque
Diagnosis
Cardiac
resonance
Review
tomography
Cardiac
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Summary:Myocardial infarction and sudden cardiac death are frequently the first manifestation of coronary artery disease.For this reason,screening of asymptomatic coronary atherosclerosis has become an attractive field of research in cardiovascular medicine.Necropsy studies have described histopathological changes associated with the development of acute coronary events.In this regard,thin-cap fibroatheroma has been identified as the main vulnerable coronary plaque feature.Hence,many imaging techniques,such as coronary computed tomography,cardiac magnetic resonance or positron emission tomography,have tried to detect noninvasively these histomorphological characteristics with different approaches.In this article,we review the role of these diagnostic tools in the detection of vulnerable coronary plaque with particular interest in their advantages and limitations as well as the clinical implications of the derived findings.
ISSN:1949-8462
1949-8462
DOI:10.4330/wjc.v8.i9.520