Supratherapeutic anti-Factor Xa levels in patients receiving prophylactic doses of enoxaparin: a case series

Highlights • anti-Factor Xa level monitoring in patients receiving prophylactic enoxaparin is increasingly common. • We report on a series of cancer patients with therapeutic or supratherapeutic anti-Factor Xa levels while on prophylactic doses of enoxaparin after surgical procedures. • Elevated ant...

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Bibliographic Details
Published in:International journal of surgery case reports 2016-01, Vol.28, p.114-116
Main Authors: Pannucci, Christopher J., MD MS, Varghese, Thomas K., MD MS, Graves, Kencee K., MD, Prazak, Ann Marie, PharmD
Format: Article
Language:English
Subjects:
Case Series
Surgery
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Summary:Highlights • anti-Factor Xa level monitoring in patients receiving prophylactic enoxaparin is increasingly common. • We report on a series of cancer patients with therapeutic or supratherapeutic anti-Factor Xa levels while on prophylactic doses of enoxaparin after surgical procedures. • Elevated anti-Factor Xa levels can result from heparin contamination of anti-Factor Xa specimens removed from central lines or chemoports. • Inappropriately drawn anti-Factor Xa levels may contribute to prophylaxis interruption or unnecessary workup for renal or liver failure.
ISSN:2210-2612
2210-2612
DOI:10.1016/j.ijscr.2016.09.034