Predicting survival of patients with idiopathic pulmonary fibrosis using GAP score: a nationwide cohort study

The clinical course of idiopathic pulmonary fibrosis (IPF) varies widely. Although the GAP model is useful for predicting mortality, survivals have not yet been validated for each GAP score. We aimed to elucidate how prognosis is related to GAP score and GAP stage in IPF patients. The Korean Interst...

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Published in:Respiratory research 2016-10, Vol.17 (1), p.131-131, Article 131
Main Authors: Lee, Sang Hoon, Kim, Song Yee, Kim, Dong Soon, Kim, Young Whan, Chung, Man Pyo, Uh, Soo Taek, Park, Choon Sik, Jeong, Sung Hwan, Park, Yong Bum, Lee, Hong Lyeol, Shin, Jong Wook, Lee, Eun Joo, Lee, Jin Hwa, Jegal, Yangin, Lee, Hyun Kyung, Kim, Yong Hyun, Song, Jin Woo, Park, Sung Woo, Park, Moo Suk
Format: Article
Language:English
Subjects:
Aged
Analysis
Care and treatment
Female
Humans
Idiopathic Pulmonary Fibrosis - diagnosis
Idiopathic Pulmonary Fibrosis - epidemiology
Idiopathic Pulmonary Fibrosis - mortality
Idiopathic Pulmonary Fibrosis - physiopathology
Kaplan-Meier Estimate
Lung - physiopathology
Male
Middle Aged
Mortality
Patient outcomes
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Pulmonary fibrosis
Republic of Korea - epidemiology
Risk Factors
Severity of Illness Index
Survival after airplane accidents, shipwrecks, etc
Time Factors
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Summary:The clinical course of idiopathic pulmonary fibrosis (IPF) varies widely. Although the GAP model is useful for predicting mortality, survivals have not yet been validated for each GAP score. We aimed to elucidate how prognosis is related to GAP score and GAP stage in IPF patients. The Korean Interstitial Lung Disease Study Group conducted a national survey to evaluate various characteristics in IPF patients from 2003 to 2007. Patients were diagnosed according to the 2002 criteria of the ATS/ERS. We enrolled 1,685 patients with IPF; 1,262 had undergone DL measurement. Patients were stratified based on GAP score (0-7): GAP score Group 0 (n = 26), Group 1 (n = 150), Group 2 (n = 208), Group 3 (n = 376), Group 4 (n = 317), Group 5 (n = 138), Group 6 (n = 39), and Group 7 (n = 8). Higher GAP score and GAP stage were associated with a poorer prognosis (p 
ISSN:1465-993X
1465-9921
1465-993X
1465-9921
DOI:10.1186/s12931-016-0454-0