Impact of spontaneous tumor rupture on prognosis of patients with T4 hepatocellular carcinoma

Background and objectives Compare the outcomes of three groups of patients with T4 hepatocellular carcinoma (HCC): tumor rupture with shock (RS group), tumor rupture without shock (R group), and no tumor rupture (NR group). Materials and Methods We retrospectively reviewed 221 patients with T4 HCC f...

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Bibliographic Details
Published in:Journal of surgical oncology 2016-06, Vol.113 (7), p.789-795
Main Authors: Chan, Wen-Hui, Hung, Chien-Fu, Pan, Kuang-Tse, Lui, Kar-Wai, Huang, Yu-Ting, Lin, Shen-Yen, Lin, Yang-Yu, Wu, Tsung-Han, Yu, Ming-Chin
Format: Article
Language:English
Subjects:
Adult
Aged
Carcinoma, Hepatocellular - diagnosis
Carcinoma, Hepatocellular - mortality
Carcinoma, Hepatocellular - pathology
Carcinoma, Hepatocellular - therapy
Combined Modality Therapy
Female
Follow-Up Studies
hepatocellular carcinoma
Hospital Mortality
Humans
Liver Neoplasms - diagnosis
Liver Neoplasms - mortality
Liver Neoplasms - pathology
Liver Neoplasms - therapy
Male
Middle Aged
Multivariate Analysis
Neoplasm Staging
Prognosis
Registries
Retrospective Studies
Rupture, Spontaneous
Shock - etiology
spontaneous tumor rupture
Survival Analysis
TNM staging system
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Summary:Background and objectives Compare the outcomes of three groups of patients with T4 hepatocellular carcinoma (HCC): tumor rupture with shock (RS group), tumor rupture without shock (R group), and no tumor rupture (NR group). Materials and Methods We retrospectively reviewed 221 patients with T4 HCC from 2010 to 2012. The clinical background and prognosis were analyzed. Results Overall in‐hospital mortality rate was 18.1%; overall median survival time was 4 months. The NR group were more likely to have multiple and infiltrative tumors (P 
ISSN:0022-4790
1096-9098
1096-9098
DOI:10.1002/jso.24245