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Association of urinary melatonin levels and aging-related outcomes in older men

Highlights • Urinary melatonin levels, measured at a single point in later life, were not associated with cognitive or physical function in this cohort of older men. • These melatonin levels also were not related to mortality, including cardiovascular-related mortality, in this cohort. • Further res...

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Published in:	Sleep medicine 2016-07, Vol.23, p.73-80
Main Authors:	Devore, Elizabeth E., ScD, Harrison, Stephanie L., MPH, Stone, Katie L., PhD, Holton, Kathleen F., PhD, Barrett-Connor, Elizabeth, MD, Ancoli-Israel, Sonia, PhD, Yaffe, Kristine, MD, Ensrud, Kristine, MD, Cawthon, Peggy M., PhD, Redline, Susan, MD, Orwoll, Eric, MD, Schernhammer, Eva S., MD
Format:	Article
Language:	English
Subjects:	Aged Aging Aging - physiology Aging - urine Cardiovascular Diseases - mortality Cognition - physiology Cognitive function Cohort Studies Humans Male Melatonin Melatonin - analogs & derivatives Melatonin - physiology Melatonin - urine Mortality Neurology Physical Fitness - physiology Physical function Sleep Medicine
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creator	Devore, Elizabeth E., ScD Harrison, Stephanie L., MPH Stone, Katie L., PhD Holton, Kathleen F., PhD Barrett-Connor, Elizabeth, MD Ancoli-Israel, Sonia, PhD Yaffe, Kristine, MD Ensrud, Kristine, MD Cawthon, Peggy M., PhD Redline, Susan, MD Orwoll, Eric, MD Schernhammer, Eva S., MD
description	Highlights • Urinary melatonin levels, measured at a single point in later life, were not associated with cognitive or physical function in this cohort of older men. • These melatonin levels also were not related to mortality, including cardiovascular-related mortality, in this cohort. • Further research should explore melatonin levels, particularly if assessed earlier in life, and other circadian markers with health aging outcomes in older men and women.
doi_str_mv	10.1016/j.sleep.2016.07.006
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subjects	Aged Aging Aging - physiology Aging - urine Cardiovascular Diseases - mortality Cognition - physiology Cognitive function Cohort Studies Humans Male Melatonin Melatonin - analogs & derivatives Melatonin - physiology Melatonin - urine Mortality Neurology Physical Fitness - physiology Physical function Sleep Medicine
title	Association of urinary melatonin levels and aging-related outcomes in older men
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