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Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs
New technology allows noninvasive measurement of total hemoglobin (Hb) in humans through use of multiple wavelength co-oximetry. This monitor is now available to the veterinary market but no studies have been performed to validate its use in animals. This study investigated the use of co-oximetry to...
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Published in: | Canadian veterinary journal 2016-11, Vol.57 (11), p.1161-1165 |
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description | New technology allows noninvasive measurement of total hemoglobin (Hb) in humans through use of multiple wavelength co-oximetry. This monitor is now available to the veterinary market but no studies have been performed to validate its use in animals. This study investigated the use of co-oximetry to measure Hb in anesthetized dogs by comparing "gold standard" Hb measurements from a laboratory (LabHb) with those measured by the co-oximeter (SpHb). Bland-Altman analysis showed that the monitor had a bias of -3.01 (SpHb values were lower than LabHb values) and that 64.5% of measured SpHb values were greater than 20 g/L different from their associated LabHb values. Based on the results of this study, use of co-oximetry to measure Hb in anesthetized dogs is not accurate enough to direct treatment. Further studies are warranted in other animal species and under other clinical conditions. |
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This monitor is now available to the veterinary market but no studies have been performed to validate its use in animals. This study investigated the use of co-oximetry to measure Hb in anesthetized dogs by comparing "gold standard" Hb measurements from a laboratory (LabHb) with those measured by the co-oximeter (SpHb). Bland-Altman analysis showed that the monitor had a bias of -3.01 (SpHb values were lower than LabHb values) and that 64.5% of measured SpHb values were greater than 20 g/L different from their associated LabHb values. Based on the results of this study, use of co-oximetry to measure Hb in anesthetized dogs is not accurate enough to direct treatment. Further studies are warranted in other animal species and under other clinical conditions.</description><identifier>ISSN: 0008-5286</identifier><identifier>PMID: 27807379</identifier><language>eng</language><publisher>Canada: Canadian Veterinary Medical Association</publisher><subject>Anesthesia - veterinary ; Animals ; Dogs ; Female ; Hemoglobins - analysis ; Male ; Monitoring, Physiologic - veterinary ; Oximetry - veterinary ; Reproducibility of Results ; Scientific</subject><ispartof>Canadian veterinary journal, 2016-11, Vol.57 (11), p.1161-1165</ispartof><rights>Copyright and/or publishing rights held by the Canadian Veterinary Medical Association 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081146/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081146/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27807379$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Read, Matt R</creatorcontrib><creatorcontrib>Rondeau, Jenna</creatorcontrib><creatorcontrib>Kwong, Grace P S</creatorcontrib><title>Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs</title><title>Canadian veterinary journal</title><addtitle>Can Vet J</addtitle><description>New technology allows noninvasive measurement of total hemoglobin (Hb) in humans through use of multiple wavelength co-oximetry. This monitor is now available to the veterinary market but no studies have been performed to validate its use in animals. This study investigated the use of co-oximetry to measure Hb in anesthetized dogs by comparing "gold standard" Hb measurements from a laboratory (LabHb) with those measured by the co-oximeter (SpHb). Bland-Altman analysis showed that the monitor had a bias of -3.01 (SpHb values were lower than LabHb values) and that 64.5% of measured SpHb values were greater than 20 g/L different from their associated LabHb values. Based on the results of this study, use of co-oximetry to measure Hb in anesthetized dogs is not accurate enough to direct treatment. Further studies are warranted in other animal species and under other clinical conditions.</description><subject>Anesthesia - veterinary</subject><subject>Animals</subject><subject>Dogs</subject><subject>Female</subject><subject>Hemoglobins - analysis</subject><subject>Male</subject><subject>Monitoring, Physiologic - veterinary</subject><subject>Oximetry - veterinary</subject><subject>Reproducibility of Results</subject><subject>Scientific</subject><issn>0008-5286</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpVkMtKw0AUhrNQbK2-gszSTWAumUs2ghRvUHCj4i6cZE7SkWSmZpJgfXoDVtHVWZyf778cJUtKqUklN2qRnMb4RinPmaInyYJrQ7XQ-TJ5fYHWWRhc8CTUxAfv_ATRTUi22IWmDaXzpEOIY48d-iGSMTrfkCqk4cN1OPR7MivAYxy2OLhPtMSGJp4lxzW0Ec8Pd5U83948re_TzePdw_p6k-64UkMKmREaqUbITZZpriytcltyXVPGa1kiQEW5YWhAsopJKi0Xc3xFJVgJTKySq2_ubiw7tNUcsYe22PWug35fBHDF_49326IJUyGpYSxTM-DyAOjD-zi3KDoXK2zbuVIYY8GMUFpwKrJZevHX69fkZ07xBe4Ecvw</recordid><startdate>201611</startdate><enddate>201611</enddate><creator>Read, Matt R</creator><creator>Rondeau, Jenna</creator><creator>Kwong, Grace P S</creator><general>Canadian Veterinary Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201611</creationdate><title>Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs</title><author>Read, Matt R ; Rondeau, Jenna ; Kwong, Grace P S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p266t-a4837e07ea9844726d0c9db27f012f5beaac0281e8a51c1505d23278605ad5a13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Anesthesia - veterinary</topic><topic>Animals</topic><topic>Dogs</topic><topic>Female</topic><topic>Hemoglobins - analysis</topic><topic>Male</topic><topic>Monitoring, Physiologic - veterinary</topic><topic>Oximetry - veterinary</topic><topic>Reproducibility of Results</topic><topic>Scientific</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Read, Matt R</creatorcontrib><creatorcontrib>Rondeau, Jenna</creatorcontrib><creatorcontrib>Kwong, Grace P S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian veterinary journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Read, Matt R</au><au>Rondeau, Jenna</au><au>Kwong, Grace P S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs</atitle><jtitle>Canadian veterinary journal</jtitle><addtitle>Can Vet J</addtitle><date>2016-11</date><risdate>2016</risdate><volume>57</volume><issue>11</issue><spage>1161</spage><epage>1165</epage><pages>1161-1165</pages><issn>0008-5286</issn><abstract>New technology allows noninvasive measurement of total hemoglobin (Hb) in humans through use of multiple wavelength co-oximetry. This monitor is now available to the veterinary market but no studies have been performed to validate its use in animals. This study investigated the use of co-oximetry to measure Hb in anesthetized dogs by comparing "gold standard" Hb measurements from a laboratory (LabHb) with those measured by the co-oximeter (SpHb). Bland-Altman analysis showed that the monitor had a bias of -3.01 (SpHb values were lower than LabHb values) and that 64.5% of measured SpHb values were greater than 20 g/L different from their associated LabHb values. Based on the results of this study, use of co-oximetry to measure Hb in anesthetized dogs is not accurate enough to direct treatment. Further studies are warranted in other animal species and under other clinical conditions.</abstract><cop>Canada</cop><pub>Canadian Veterinary Medical Association</pub><pmid>27807379</pmid><tpages>5</tpages></addata></record> |
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subjects | Anesthesia - veterinary Animals Dogs Female Hemoglobins - analysis Male Monitoring, Physiologic - veterinary Oximetry - veterinary Reproducibility of Results Scientific |
title | Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs |
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