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Beneficial Effects of UV-Radiation: Vitamin D and beyond

Aside from its well-known effects on bone and mineral metabolism, vitamin D may also play an important role in extra-skeletal processes like immunologic diseases, cancer, or cardiovascular diseases. Even though meta-analyses showed that vitamin D supplementation reduces fractures, falls, and overall...

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Published in:International journal of environmental research and public health 2016-10, Vol.13 (10), p.1028
Main Authors: Trummer, Christian, Pandis, Marlene, Verheyen, Nicolas, Grübler, Martin R, Gaksch, Martin, Obermayer-Pietsch, Barbara, Tomaschitz, Andreas, Pieber, Thomas R, Pilz, Stefan, Schwetz, Verena
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cited_by cdi_FETCH-LOGICAL-c390t-72e2751e820e3aa4cbd9b265711d138d65500c684a580919596fdc1d5fbdf9873
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container_issue 10
container_start_page 1028
container_title International journal of environmental research and public health
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creator Trummer, Christian
Pandis, Marlene
Verheyen, Nicolas
Grübler, Martin R
Gaksch, Martin
Obermayer-Pietsch, Barbara
Tomaschitz, Andreas
Pieber, Thomas R
Pilz, Stefan
Schwetz, Verena
description Aside from its well-known effects on bone and mineral metabolism, vitamin D may also play an important role in extra-skeletal processes like immunologic diseases, cancer, or cardiovascular diseases. Even though meta-analyses showed that vitamin D supplementation reduces fractures, falls, and overall mortality, its potential benefits did not find universal acclaim. Several health care authorities published Recommended Dietary Allowances (RDAs) for vitamin D, most of them ranging from 600 to 800 international units (IU) per day, corresponding to a serum level of 25-hydroxyvitamin D of at least 20 ng/mL (50 nmol/L). However, studies conducted in the general population revealed a much lower overall intake of vitamin D than the proposed RDAs. Thus, strategies to increase the vitamin D intake in the general population, e.g., food fortification or vitamin D supplementation, are needed to match the existing evidence and recommendations. Therefore, several currently ongoing projects aim to investigate the effect of vitamin D supplementation in the general population and try to establish food-based solutions to improve vitamin D status.
doi_str_mv 10.3390/ijerph13101028
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source PubMed (Medline); Publicly Available Content Database; Free Full-Text Journals in Chemistry
subjects Accidental Falls
Bone and Bones
Dietary Supplements
Food, Fortified
Humans
Review
Ultraviolet Rays
Vitamin D - analogs & derivatives
Vitamin D - metabolism
Vitamin D - radiation effects
Vitamin D Deficiency - blood
title Beneficial Effects of UV-Radiation: Vitamin D and beyond
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