Holographic tomography with scanning of illumination: space-domain reconstruction for spatially invariant accuracy

The paper presents two novel, space-domain reconstruction algorithms for holographic tomography utilizing scanning of illumination and a fixed detector that is highly suitable for imaging of living biomedical specimens. The first proposed algorithm is an adaptation of the filtered backpropagation to...

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Bibliographic Details
Published in:Biomedical optics express 2016-10, Vol.7 (10), p.4086-4101
Main Authors: Kostencka, Julianna, Kozacki, Tomasz, Kuś, Arkadiusz, Kemper, Björn, Kujawińska, Małgorzata
Format: Article
Language:English
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Summary:The paper presents two novel, space-domain reconstruction algorithms for holographic tomography utilizing scanning of illumination and a fixed detector that is highly suitable for imaging of living biomedical specimens. The first proposed algorithm is an adaptation of the filtered backpropagation to the scanning illumination tomography. Its space-domain implementation enables avoiding the error-prone interpolation in the Fourier domain, which is a significant problem of the state-of-the-art tomographic algorithm. The second proposed algorithm is a modified version of the former, which ensures the spatially invariant reconstruction accuracy. The utility of the proposed algorithms is demonstrated with numerical simulations and experimental measurement of a cancer cell.
ISSN:2156-7085
2156-7085
DOI:10.1364/BOE.7.004086