Circulating cathodic antigen cassette test versus haematuria strip test in diagnosis of urinary schistosomiasis

Urinary schistosomiasis caused by Schistosoma haematobium constitutes a major public health problem in many tropical and sub-tropical countries. This study was conducted to evaluate circulating cathodic antigen cassette test and haematuria strip test for detection of S. haematobium in urine samples...

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Bibliographic Details
Published in:Journal of parasitic diseases 2016-12, Vol.40 (4), p.1193-1198
Main Authors: El-Ghareeb, Azza S., Abd El Motaleb, Ghada S., Waked, Nevien Maher, Osman Hany Kamel, Nancy, Aly, Nagwa Shaban
Format: Article
Language:English
Subjects:
Antigens
Eggs
Health Promotion and Disease Prevention
Hematuria
Infectious Diseases
Mapping
Medicine
Medicine & Public Health
Microscopy
Original
Original Article
Population studies
Public health
Schistosoma haematobium
Schistosomiasis
schistosomiasis haematobia
screening
Statistical analysis
Urine
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Summary:Urinary schistosomiasis caused by Schistosoma haematobium constitutes a major public health problem in many tropical and sub-tropical countries. This study was conducted to evaluate circulating cathodic antigen cassette test and haematuria strip test for detection of S. haematobium in urine samples and to evaluate their screening performance among the study population. Microscopy was used as a gold standard. A total of 600 urine samples were examined by microscopy for detection of S. haematobium eggs, screened for microhaematuria using Self-Stik reagent strips and screened for circulating cathodic antigen (CCA) using the urine-CCA cassette test. The specificity of CCA, microhaematuria and macrohaematuria was 96.4, 40.6 and 31.2 % respectively while the sensitivity was 88.2, 99.3 and 100 % respectively which was statistically significant (P 
ISSN:0971-7196
0975-0703
DOI:10.1007/s12639-015-0648-2