Pre-operative clinical and instrumental factors as antireflux surgery outcome predictors

Gastroesophageal reflux disease (GERD) is nowadays a highly prevalent, chronic condition, with 10% to 30% of Western populations affected by weekly symptoms.Many patients with mild reflux symptoms are treated adequately with lifestyle modifications, dietary changes,and low-dose proton pump inhibitor...

Full description

Saved in:
Bibliographic Details
Published in:World journal of gastrointestinal surgery 2016-11, Vol.8 (11), p.719-728
Main Authors: Tolone, Salvatore, Gualtieri, Giorgia, Savarino, Edoardo, Frazzoni, Marzio, de Bortoli, Nicola, Furnari, Manuele, Casalino, Giuseppina, Parisi, Simona, Savarino, Vincenzo, Docimo, Ludovico
Format: Article
Language:English
Subjects:
Antireflux
disease
Fundoplication
Gastroesophageal
High
ImpedancepH
manometry
monitoring
Nissen
Laparoscopy
Outcome
predictors
reflux
resolution
Review
surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Gastroesophageal reflux disease (GERD) is nowadays a highly prevalent, chronic condition, with 10% to 30% of Western populations affected by weekly symptoms.Many patients with mild reflux symptoms are treated adequately with lifestyle modifications, dietary changes,and low-dose proton pump inhibitors (PPIs). For those with refractory GERD poorly controlled with daily PPIs,numerous treatment options exist. Fundoplication is currently the most commonly performed antireflux operation for management of GERD. Outcomes described in current literature following laparoscopic fundoplication indicate that it is highly effective for treatment of GERD;early clinical studies demonstrate relief of symptoms in approximately 85%-90% of patients. However it is still unclear which factors, clinical or instrumental,are able to predict a good outcome after surgery.Virtually all demographic, esophagogastric junction anatomic conditions, as well as instrumental (such as presence of esophagitis at endoscopy, or motility patterns determined by esophageal high resolution manometry or reflux patterns determined by means of pH/impedance-pH monitoring) and clinical features (such as typical or atypical symptoms presence) of patients undergoing laparoscopic fundoplication for GERD can be factors associated with symptomatic relief. With this in mind, we sought to review studies that identified the factors that predict outcome after laparoscopic total fundoplication.
ISSN:1948-9366
1948-9366
DOI:10.4240/wjgs.v8.i11.719