Can we apply the MRI BI-RADS lexicon morphology descriptors on contrast-enhanced spectral mammography?

• Published in: British journal of radiology 2016-08, Vol.89 (1064), p.20160157-20160157
• Main Authors: Kamal, Rasha M, Helal, Maha H, Mansour, Sahar M, Haggag, Marwa A, Nada, Omniya M, Farahat, Iman G, Alieldin, Nelly H
• Format: Article
• Language: English
• Subjects: Breast
• ISSN: 0007-1285; 1748-880X
• DOI: 10.1259/bjr.20160157

To assess the feasibility of using the MRI breast imaging reporting and data system (BI-RADS) lexicon morphology descriptors to characterize enhancing breast lesions identified on contrast-enhanced spectral mammography (CESM). The study is a retrospective analysis of the morphology descriptors of 261 enhancing breast lesions identified on CESM in 239 patients. We presented the morphological categorization of the included lesions into focus, mass and non-mass. Further classifications included (1) the multiplicity for "focus" category, (2) the shape, margin and internal enhancement for "mass" category and (3) the distribution and internal enhancement for "non-mass" category. Each morphology descriptor was evaluated individually (irrespective of all other descriptors) by calculating its sensitivity, specificity, positive-predictive value (PPV) and negative-predictive value (NPV) and likelihood ratios (LRs). The study included 68/261 (26.1%) benign lesions and 193/261 (73.9%) malignant lesions. Intensely enhancing foci, whether single (7/12, 58.3%) or multiple (2/12, 16.7%), were malignant. Descriptors of "irregular"-shape (PPV: 92.4%) and "non-circumscribed" margin (odds ratio: 55.2, LR positive: 4.77; p-value: