Carrion's disease: an eradicable illness?

Carrion's disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion's disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related t...

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Bibliographic Details
Published in:Infectious diseases of poverty 2016-12, Vol.5 (1), p.105-105, Article 105
Main Authors: Gomes, Cláudia, Pons, Maria J, Del Valle Mendoza, Juana, Ruiz, Joaquim
Format: Article
Language:English
Subjects:
Amèrica del Sud
Analysis
Bartonella bacilliformis - physiology
Bartonella Infections - microbiology
Bartonella Infections - prevention & control
Colombia
Communicable diseases
Ecuador
Epidemics
Epidemiology
Health aspects
Humans
Infectious diseases
Malalties infeccioses
Medicina tropical
Neglected Diseases - microbiology
Neglected Diseases - prevention & control
Peru
South America
Tropical medicine
Verruga peruana
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Summary:Carrion's disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion's disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion's disease in endemic areas, they make take into account due to they are the perpetuators of this disease. The actual scenario of Carrion's disease, in which the illness is arriving to new areas, due to the expansion of the vector's distribution, suggests that now may be a crucial time to design a strategy focusing on its elimination.
ISSN:2049-9957
2095-5162
2049-9957
DOI:10.1186/s40249-016-0197-7