Epithelial ovarian cancer inherent resistance: May the pleiotropic interaction between reduced immunosurveillance and drug-resistant cells play a key role?

Highlights • Cancer cells may have inherent chemoresistance which allows an indefinite expansion . • Transformed ovarian epithelial cells may undergo an immunoediting process . • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy .

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Bibliographic Details
Published in:Gynecologic oncology reports 2016-11, Vol.18, p.57-58
Main Authors: Laganà, Antonio Simone, Sofo, Vincenza, Vitale, Salvatore Giovanni, Triolo, Onofrio
Format: Article
Language:English
Subjects:
Correspondence
Hematology, Oncology and Palliative Medicine
Obstetrics and Gynecology
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Description
Summary:Highlights • Cancer cells may have inherent chemoresistance which allows an indefinite expansion . • Transformed ovarian epithelial cells may undergo an immunoediting process . • Immunoedited ovarian cancer drug-resistant cells escape first-line chemotherapy .
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2016.09.004