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Racial/Ethnic Differences in the Association of Childhood Adversities with Depression and the Role of Resilience
Abstract Background Adverse childhood experiences (ACE) including childhood abuse and trauma increase depressive symptoms. The role of resilience and how it interacts with both ACEs and the potential development of depressive symptoms, including how race and ethnicity moderate these effects, are muc...
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Published in: | Journal of affective disorders 2017-01, Vol.208, p.577-581 |
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container_title | Journal of affective disorders |
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description | Abstract Background Adverse childhood experiences (ACE) including childhood abuse and trauma increase depressive symptoms. The role of resilience and how it interacts with both ACEs and the potential development of depressive symptoms, including how race and ethnicity moderate these effects, are much less studied. The aims of this study were to examine: 1) whether there is a dose-response relationship between trauma and depressive symptoms; 2) whether early trauma affected European Americans (EA) and African Americans (AA) in a similar fashion; and 3) whether resilience mitigates the effect of trauma. Methods The present study comprised a cross-sectional study of subjects from a longitudinal cohort. All subjects were 19 years or older with traumatic experiences prior to age 18. Subjects were assessed for depressive symptoms as well as resilience. Results In 413 subjects enrolled, ACEs were significantly associated with depression severity in a dose-response fashion (p |
doi_str_mv | 10.1016/j.jad.2016.10.024 |
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Vaughn ; Su, Shaoyong</creator><creatorcontrib>Youssef, Nagy A ; Belew, Daniel ; Hao, Guang ; Wang, Xiaoling ; Treiber, Frank A ; Stefanek, Michael ; Yassa, Mark ; Boswell, Elizabeth ; McCall, W. Vaughn ; Su, Shaoyong</creatorcontrib><description>Abstract Background Adverse childhood experiences (ACE) including childhood abuse and trauma increase depressive symptoms. The role of resilience and how it interacts with both ACEs and the potential development of depressive symptoms, including how race and ethnicity moderate these effects, are much less studied. The aims of this study were to examine: 1) whether there is a dose-response relationship between trauma and depressive symptoms; 2) whether early trauma affected European Americans (EA) and African Americans (AA) in a similar fashion; and 3) whether resilience mitigates the effect of trauma. Methods The present study comprised a cross-sectional study of subjects from a longitudinal cohort. All subjects were 19 years or older with traumatic experiences prior to age 18. Subjects were assessed for depressive symptoms as well as resilience. Results In 413 subjects enrolled, ACEs were significantly associated with depression severity in a dose-response fashion (p<0.001). Notably, AAs had lower depression scores at low to moderate levels of ACEs than EAs, but reported comparable levels of depression with severe exposure to ACEs (pInteraction=0.05). In both EAs and AAs, young adults with high and medium levels of resilience showed less depressive symptoms compared to those with low resilience (p<0.05). Limitations to consider are the cross-sectional design, possibility of other confounders, and potential for recall bias of this study. Conclusion While ACEs were significantly associated with severity of depression in a dose-response fashion, higher resilience mitigated the impact of childhood adversities on depressive symptoms in young adults. The results are encouraging, and guides research for therapeutics to boost resilience.</description><identifier>ISSN: 0165-0327</identifier><identifier>EISSN: 1573-2517</identifier><identifier>DOI: 10.1016/j.jad.2016.10.024</identifier><identifier>PMID: 27806896</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adult ; Adult Survivors of Child Adverse Events - psychology ; Adverse childhood experiences ; Black or African American ; Child ; Child Abuse - ethnology ; Child Abuse - psychology ; Cross-Sectional Studies ; Depression - ethnology ; Depression - etiology ; Depressive symptoms ; Female ; Humans ; Male ; Psychiatry ; Race/ethnicity ; Resilience ; Surveys and Questionnaires ; White People ; Young Adult</subject><ispartof>Journal of affective disorders, 2017-01, Vol.208, p.577-581</ispartof><rights>2016 Elsevier B.V.</rights><rights>Copyright © 2016 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c506t-7016f6095305fa39870715af56fc9c74440d3bedbfe4c54bdf104fbcf91f1b023</citedby><cites>FETCH-LOGICAL-c506t-7016f6095305fa39870715af56fc9c74440d3bedbfe4c54bdf104fbcf91f1b023</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27806896$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Youssef, Nagy A</creatorcontrib><creatorcontrib>Belew, Daniel</creatorcontrib><creatorcontrib>Hao, Guang</creatorcontrib><creatorcontrib>Wang, Xiaoling</creatorcontrib><creatorcontrib>Treiber, Frank A</creatorcontrib><creatorcontrib>Stefanek, Michael</creatorcontrib><creatorcontrib>Yassa, Mark</creatorcontrib><creatorcontrib>Boswell, Elizabeth</creatorcontrib><creatorcontrib>McCall, W. Vaughn</creatorcontrib><creatorcontrib>Su, Shaoyong</creatorcontrib><title>Racial/Ethnic Differences in the Association of Childhood Adversities with Depression and the Role of Resilience</title><title>Journal of affective disorders</title><addtitle>J Affect Disord</addtitle><description>Abstract Background Adverse childhood experiences (ACE) including childhood abuse and trauma increase depressive symptoms. The role of resilience and how it interacts with both ACEs and the potential development of depressive symptoms, including how race and ethnicity moderate these effects, are much less studied. The aims of this study were to examine: 1) whether there is a dose-response relationship between trauma and depressive symptoms; 2) whether early trauma affected European Americans (EA) and African Americans (AA) in a similar fashion; and 3) whether resilience mitigates the effect of trauma. Methods The present study comprised a cross-sectional study of subjects from a longitudinal cohort. All subjects were 19 years or older with traumatic experiences prior to age 18. Subjects were assessed for depressive symptoms as well as resilience. Results In 413 subjects enrolled, ACEs were significantly associated with depression severity in a dose-response fashion (p<0.001). Notably, AAs had lower depression scores at low to moderate levels of ACEs than EAs, but reported comparable levels of depression with severe exposure to ACEs (pInteraction=0.05). In both EAs and AAs, young adults with high and medium levels of resilience showed less depressive symptoms compared to those with low resilience (p<0.05). Limitations to consider are the cross-sectional design, possibility of other confounders, and potential for recall bias of this study. Conclusion While ACEs were significantly associated with severity of depression in a dose-response fashion, higher resilience mitigated the impact of childhood adversities on depressive symptoms in young adults. The results are encouraging, and guides research for therapeutics to boost resilience.</description><subject>Adult</subject><subject>Adult Survivors of Child Adverse Events - psychology</subject><subject>Adverse childhood experiences</subject><subject>Black or African American</subject><subject>Child</subject><subject>Child Abuse - ethnology</subject><subject>Child Abuse - psychology</subject><subject>Cross-Sectional Studies</subject><subject>Depression - ethnology</subject><subject>Depression - etiology</subject><subject>Depressive symptoms</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Psychiatry</subject><subject>Race/ethnicity</subject><subject>Resilience</subject><subject>Surveys and Questionnaires</subject><subject>White People</subject><subject>Young Adult</subject><issn>0165-0327</issn><issn>1573-2517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp9Uk1v1DAUtBCILoUfwAXlyCVbO47tREiVVttCK1WqtIWz5djPxMEbL3Z2q_57nG6pgAMnf7yZeU8zD6H3BC8JJvxsWA7KLKt8ze8lruoXaEGYoGXFiHiJFrnASkwrcYLepDRgjHkr8Gt0UokG86blC7TbKO2UP7uc-tHp4sJZCxFGDalwYzH1UKxSChkyuTAWwRbr3nnTh2CKlTlATG5yGXvvpr64gF2ElGagGs0jeRM8zKwNJOfdrPsWvbLKJ3j3dJ6ib58vv66vypvbL9fr1U2pGeZTKfLsluOWUcysom0jsCBMWcatbrWo6xob2oHpLNSa1Z2xBNe207YllnS4oqfo_Ki723dbMBrGKSovd9FtVXyQQTn5d2V0vfweDpIRVjcNzwIfnwRi-LmHNMmtSxq8VyOEfZKkoVxkbyuSoeQI1TGkFME-tyFYzknJQeak5JzU_JWTypwPf873zPgdTQZ8OgIgu3RwEGXSjw4aF0FP0gT3X_nzf9jau5yw8j_gAdIQ9nHM9ksiUyWxvJtXZd4UwinBoqH0FzRourM</recordid><startdate>20170115</startdate><enddate>20170115</enddate><creator>Youssef, Nagy A</creator><creator>Belew, Daniel</creator><creator>Hao, Guang</creator><creator>Wang, Xiaoling</creator><creator>Treiber, Frank A</creator><creator>Stefanek, Michael</creator><creator>Yassa, Mark</creator><creator>Boswell, Elizabeth</creator><creator>McCall, W. Vaughn</creator><creator>Su, Shaoyong</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170115</creationdate><title>Racial/Ethnic Differences in the Association of Childhood Adversities with Depression and the Role of Resilience</title><author>Youssef, Nagy A ; Belew, Daniel ; Hao, Guang ; Wang, Xiaoling ; Treiber, Frank A ; Stefanek, Michael ; Yassa, Mark ; Boswell, Elizabeth ; McCall, W. Vaughn ; Su, Shaoyong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c506t-7016f6095305fa39870715af56fc9c74440d3bedbfe4c54bdf104fbcf91f1b023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Adult Survivors of Child Adverse Events - psychology</topic><topic>Adverse childhood experiences</topic><topic>Black or African American</topic><topic>Child</topic><topic>Child Abuse - ethnology</topic><topic>Child Abuse - psychology</topic><topic>Cross-Sectional Studies</topic><topic>Depression - ethnology</topic><topic>Depression - etiology</topic><topic>Depressive symptoms</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Psychiatry</topic><topic>Race/ethnicity</topic><topic>Resilience</topic><topic>Surveys and Questionnaires</topic><topic>White People</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Youssef, Nagy A</creatorcontrib><creatorcontrib>Belew, Daniel</creatorcontrib><creatorcontrib>Hao, Guang</creatorcontrib><creatorcontrib>Wang, Xiaoling</creatorcontrib><creatorcontrib>Treiber, Frank A</creatorcontrib><creatorcontrib>Stefanek, Michael</creatorcontrib><creatorcontrib>Yassa, Mark</creatorcontrib><creatorcontrib>Boswell, Elizabeth</creatorcontrib><creatorcontrib>McCall, W. Vaughn</creatorcontrib><creatorcontrib>Su, Shaoyong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of affective disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Youssef, Nagy A</au><au>Belew, Daniel</au><au>Hao, Guang</au><au>Wang, Xiaoling</au><au>Treiber, Frank A</au><au>Stefanek, Michael</au><au>Yassa, Mark</au><au>Boswell, Elizabeth</au><au>McCall, W. Vaughn</au><au>Su, Shaoyong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Racial/Ethnic Differences in the Association of Childhood Adversities with Depression and the Role of Resilience</atitle><jtitle>Journal of affective disorders</jtitle><addtitle>J Affect Disord</addtitle><date>2017-01-15</date><risdate>2017</risdate><volume>208</volume><spage>577</spage><epage>581</epage><pages>577-581</pages><issn>0165-0327</issn><eissn>1573-2517</eissn><abstract>Abstract Background Adverse childhood experiences (ACE) including childhood abuse and trauma increase depressive symptoms. The role of resilience and how it interacts with both ACEs and the potential development of depressive symptoms, including how race and ethnicity moderate these effects, are much less studied. The aims of this study were to examine: 1) whether there is a dose-response relationship between trauma and depressive symptoms; 2) whether early trauma affected European Americans (EA) and African Americans (AA) in a similar fashion; and 3) whether resilience mitigates the effect of trauma. Methods The present study comprised a cross-sectional study of subjects from a longitudinal cohort. All subjects were 19 years or older with traumatic experiences prior to age 18. Subjects were assessed for depressive symptoms as well as resilience. Results In 413 subjects enrolled, ACEs were significantly associated with depression severity in a dose-response fashion (p<0.001). Notably, AAs had lower depression scores at low to moderate levels of ACEs than EAs, but reported comparable levels of depression with severe exposure to ACEs (pInteraction=0.05). In both EAs and AAs, young adults with high and medium levels of resilience showed less depressive symptoms compared to those with low resilience (p<0.05). Limitations to consider are the cross-sectional design, possibility of other confounders, and potential for recall bias of this study. Conclusion While ACEs were significantly associated with severity of depression in a dose-response fashion, higher resilience mitigated the impact of childhood adversities on depressive symptoms in young adults. The results are encouraging, and guides research for therapeutics to boost resilience.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>27806896</pmid><doi>10.1016/j.jad.2016.10.024</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Adult Survivors of Child Adverse Events - psychology Adverse childhood experiences Black or African American Child Child Abuse - ethnology Child Abuse - psychology Cross-Sectional Studies Depression - ethnology Depression - etiology Depressive symptoms Female Humans Male Psychiatry Race/ethnicity Resilience Surveys and Questionnaires White People Young Adult |
title | Racial/Ethnic Differences in the Association of Childhood Adversities with Depression and the Role of Resilience |
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