Validated adherence scales used in a measurement-guided medication management approach to target and tailor a medication adherence intervention: a randomised controlled trial

ObjectiveTo determine if a targeted and tailored intervention based on a discussion informed by validated adherence scales will improve medication adherence.DesignProspective randomised trial.Setting2 community pharmacies in Brisbane, Australia.MethodsPatients recently initiated on a cardiovascular...

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Bibliographic Details
Published in:BMJ open 2016-11, Vol.6 (11), p.e013375-e013375
Main Authors: Nguyen, Thi-My-Uyen, La Caze, Adam, Cottrell, Neil
Format: Article
Language:English
Subjects:
Antihypertensive Agents - therapeutic use
Australia - epidemiology
Clinical outcomes
Community Pharmacy Services
Diabetes
Drug dosages
Drug stores
Drug Utilization Review
Electronic monitoring
Female
Health Services Research
Humans
Hypertension
Hypoglycemic Agents - therapeutic use
Intervention
Interviews
Male
Medication Adherence - statistics & numerical data
Medicine
Middle Aged
Patient Acceptance of Health Care - statistics & numerical data
Pharmaceuticals
Pharmacists
Precision Medicine
Questionnaires
Researchers
Studies
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Summary:ObjectiveTo determine if a targeted and tailored intervention based on a discussion informed by validated adherence scales will improve medication adherence.DesignProspective randomised trial.Setting2 community pharmacies in Brisbane, Australia.MethodsPatients recently initiated on a cardiovascular or oral hypoglycaemic medication within the past 4–12 weeks were recruited from two community pharmacies. Participants identified as non-adherent using the Medication Adherence Questionnaire (MAQ) were randomised into the intervention or control group. The intervention group received a tailored intervention based on a discussion informed by responses to the MAQ, Beliefs about Medicines Questionnaire-Specific and Brief Illness Perception Questionnaire. Adherence was measured using the MAQ at 3 and 6 months following the intervention.ResultsA total of 408 patients were assessed for eligibility, from which 152 participants were enrolled into the study. 120 participants were identified as non-adherent using the MAQ and randomised to the ‘intervention’ or ‘control’ group. The mean MAQ score at baseline in the intervention and control were similar (1.58: 95% CI (1.38 to 1.78) and 1.60: 95% CI (1.43 to 1.77), respectively). There was a statistically significant improvement in adherence in the intervention group compared to control at 3 months (mean MAQ score 0.42: 95% CI (0.27 to 0.57) vs 1.58: 95% CI (1.42 to 1.75); p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2016-013375