Pathophysiology of Non Alcoholic Fatty Liver Disease

The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathoph...

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Bibliographic Details
Published in:International journal of molecular sciences 2016-12, Vol.17 (12), p.2082-2082
Main Authors: Petta, Salvatore, Gastaldelli, Amalia, Rebelos, Eleni, Bugianesi, Elisabetta, Messa, Piergiorgio, Miele, Luca, Svegliati-Baroni, Gianluca, Valenti, Luca, Bonino, Ferruccio
Format: Article
Language:English
Subjects:
Adipose Tissue - metabolism
Cholesterol
Fatty acids
Gastrointestinal Hormones - metabolism
Humans
Insulin resistance
Lipids - blood
Muscles - metabolism
Non-alcoholic Fatty Liver Disease - blood
Non-alcoholic Fatty Liver Disease - physiopathology
Pancreatic Hormones - metabolism
Peptides
Review
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Summary:The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathophysiological interplay among major circulating effectors/mediators of fatty liver, such as circulating lipids, mediators released by adipose, muscle and liver tissues and pancreatic and gut hormones in relation to diet, exercise and inflammation.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms17122082