Factors predicting venous thromboembolism after spine surgery

• Published in: Medicine (Baltimore) 2016-12, Vol.95 (52), p.e5776-e5776
• Main Authors: Wang, Tao, Yang, Si-Dong, Huang, Wen-Zheng, Liu, Feng-Yu, Wang, Hui, Ding, Wen-Yuan
• Format: Article
• Language: English
• Subjects: Asian Continental Ancestry Group - statistics & numerical data; Diabetes Mellitus - epidemiology; European Continental Ancestry Group - statistics & numerical data; Humans; Incidence; Lumbar Vertebrae; Mobility Limitation; Postoperative Complications - epidemiology; Risk Factors; Spinal Diseases - surgery; Stockings, Compression - statistics & numerical data; Systematic Review and Meta-Analysis; Venous Thromboembolism - epidemiology; Walking - physiology
• ISSN: 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000005776

A meta-analysis was performed to explore predicted factors of venous thromboembolism (VTE) after surgery in the treatment for spine degeneration diseases. Many scholars have focused on VTE after spine surgery, but as for the risk factors of VTE have not reached a consensus. An extensive search of literature, "spine or spinal," "degeneration," "after surgery or postoperation," and "venous thromboembolism" as key words, was performed in PubMed/MEDLINE, Embase, the Cochrane library, CNKI, and WANFANG databases. The following variables were extracted: wearing elastic stocking, hypertension (HT), heart disease, diabetes, drinking, anticoagulant therapy, walking disability preoperation, smoking, sex, age, surgical duration, fusion versus nonfusion (lumbar fusion vs lumbar discectomy), surgical site (cervical vs lumbar), blood loss, and body mass index. Data analysis was conducted with RevMan 5.3 and STATA 12.0. A total of 12 studies were identified, including 34,597 patients of whom 624 patients had VTE, and the incidence of VTE was 2% in all patients who underwent spine surgery. The incidence of VTE for Asian patients was 7.5%, compared with 1% VTE for Occidental patients; the difference was significant (P