The predictive value of mitral leaflet motion and thickness index scores on early restenosis after mitral balloon valvuloplasty

The purpose of this study was to investigate whether there is any association between mitral leaflet motion (LMI) and leaflet thickness index (LTI) scores and the rate of restenosis 3 months after successful mitral balloon valvuloplasty. The study population consisted of 46 patients with symptomatic...

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Published in:Texas Heart Institute journal 2004, Vol.31 (3), p.251-256
Main Authors: Akin, Mustafa, Sagcan, Abdi, Nalbantgil, Sanem, Ozerkan, Filiz, Akilli, Azem, Oguz, Yavuzgil, Zoghi, Mehdi
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Catheterization
Clinical Investigation
Female
Follow-Up Studies
Humans
Male
Middle Aged
Mitral Valve - diagnostic imaging
Mitral Valve - pathology
Mitral Valve - physiopathology
Mitral Valve Stenosis - pathology
Mitral Valve Stenosis - physiopathology
Mitral Valve Stenosis - therapy
Prognosis
Recurrence
Rheumatic Heart Disease - pathology
Rheumatic Heart Disease - physiopathology
Rheumatic Heart Disease - therapy
Severity of Illness Index
Ultrasonography
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Summary:The purpose of this study was to investigate whether there is any association between mitral leaflet motion (LMI) and leaflet thickness index (LTI) scores and the rate of restenosis 3 months after successful mitral balloon valvuloplasty. The study population consisted of 46 patients with symptomatic rheumatic mitral stenosis who underwent balloon valvuloplasty (37 women, 9 men; mean age, 36 +/- 9 years). Two-dimensional and Doppler echocardiography were performed in all patients on the day before, immediately after, and 3 months after valvuloplasty. The severity of restriction of leaflet motion and the severity of leaflet thickening were classified into grades of mild (a score of 0), moderate (a score of 1), and severe (a score of 2). Subvalvular disease and commissural involvement were homogeneous in all patients. Before and immediately after mitral balloon valvuloplasty, there were no significant differences in mitral valve area among the groups with different LMI and LTI scores. However, at 3 months after valvuloplasty, reduction in mitral valve area was more significant in patients who had higher pre-procedural LMI and LTI scores (P < 0.05). The rates of early restenosis were 0 with a total score of 0, 14.2% with a total score of 1-2, and 32% with a total score of 3. In conclusion, quantitative assessment of LMI and LTI scores by 2-dimensional echocardiography may be helpful in predicting early restenosis after mitral balloon valvuloplasty. Early reduction in mitral valve area is significant in patients who have higher total LMI and LTI scores.
ISSN:0730-2347